Abstract
Accumulation of mutant topoisomerase I cleavage complex can lead to SOS induction and cell death in Escherichia coli. The single-stranded break associated with mutant topoisomerase I cleavage complex is converted to double-stranded break, which then is processed by the RecBCD pathway, followed by association of RecA with the single-stranded DNA.
Original language | English (US) |
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Pages (from-to) | 3399-3403 |
Number of pages | 5 |
Journal | Journal of Bacteriology |
Volume | 190 |
Issue number | 9 |
DOIs | |
State | Published - May 2008 |
Externally published | Yes |
ASJC Scopus subject areas
- Microbiology
- Molecular Biology