Some new observations in an intracranial germinoma

Asao Hirano, Josefina F. Llena, Hyung D. Chung

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


A case of an intracranial germinoma from the suprasellar region of a 9-year-old girl was examined in the electron microscope. The tumor consists, for the most part, of both large polygonal and small lymphocyte-like elements. Annulate lamellae are common in the epithelial cells. The small blood vessels are fenestrated, and the endothelial cells contain tubular bodies, membrane-bounded vacuoles containing dense fluid and occasional tubules, arrays of tubules within the nuclear envelope and rough endoplasmic reticulum, and a markedly irregular luminal surface. Dense, lamellated structures are present in the widened, collagen-containing perivascular spaces.

Original languageEnglish (US)
Pages (from-to)103-113
Number of pages11
JournalActa neuropathologica
Issue number2
StatePublished - Jun 1 1975


  • Annulate Lamellae
  • Fenestrae
  • Germinoma
  • Tubular Array
  • Tubular Bodies

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Clinical Neurology
  • Cellular and Molecular Neuroscience


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