Solving the organ shortage crisis

The 7th Annual American Society of Transplant Surgeons' State-of-the-Art Winter Symposium

E. A. Pomfret, R. S. Sung, J. Allan, Milan Kinkhabwala, J. K. Melancon, J. P. Roberts

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

The 2007 American Society of Transplant Surgeons' (ASTS) State-of-the-Art Winter Symposium entitled, 'Solving the Organ Shortage Crisis' explored ways to increase the supply of donor organs to meet the challenge of increasing waiting lists and deaths while awaiting transplantation. While the increasing use of organs previously considered marginal, such as those from expanded criteria donors (ECD) or donors after cardiac death (DCD) has increased the number of transplants from deceased donors, these transplants are often associated with inferior outcomes and higher costs. The need remains for innovative ways to increase both deceased and living donor transplants. In addition to increasing ECD and DCD utilization, increasing use of deceased donors with certain types of infections such as Hepatitis B and C, and increasing use of living donor liver, lung and intestinal transplants may also augment the organ supply. The extent by which donors may be offered incentives for donation, and the practical, ethical and legal implications of compensating organ donors were also debated. The expanded use of nonstandard organs raises potential ethical considerations about appropriate recipient selection, informed consent and concerns that the current regulatory environment discourages and penalizes these efforts.

Original languageEnglish (US)
Pages (from-to)745-752
Number of pages8
JournalAmerican Journal of Transplantation
Volume8
Issue number4
DOIs
StatePublished - Apr 2008

Fingerprint

Tissue Donors
Living Donors
Transplants
Waiting Lists
Hepatitis C
Hepatitis B
Informed Consent
Motivation
Transplantation
Costs and Cost Analysis
Lung
Liver
Infection

Keywords

  • Access to transplantation
  • Deceased donor kidneys
  • Deceased donor organs
  • Donor/recipient matching
  • Ethics
  • Expanded criteria donors
  • Live donor transplantation
  • Organ donation
  • Organ sales
  • Organ shortage

ASJC Scopus subject areas

  • Immunology

Cite this

Solving the organ shortage crisis : The 7th Annual American Society of Transplant Surgeons' State-of-the-Art Winter Symposium. / Pomfret, E. A.; Sung, R. S.; Allan, J.; Kinkhabwala, Milan; Melancon, J. K.; Roberts, J. P.

In: American Journal of Transplantation, Vol. 8, No. 4, 04.2008, p. 745-752.

Research output: Contribution to journalArticle

@article{ca84f9428ddb4dcb9322e18ca5294d0d,
title = "Solving the organ shortage crisis: The 7th Annual American Society of Transplant Surgeons' State-of-the-Art Winter Symposium",
abstract = "The 2007 American Society of Transplant Surgeons' (ASTS) State-of-the-Art Winter Symposium entitled, 'Solving the Organ Shortage Crisis' explored ways to increase the supply of donor organs to meet the challenge of increasing waiting lists and deaths while awaiting transplantation. While the increasing use of organs previously considered marginal, such as those from expanded criteria donors (ECD) or donors after cardiac death (DCD) has increased the number of transplants from deceased donors, these transplants are often associated with inferior outcomes and higher costs. The need remains for innovative ways to increase both deceased and living donor transplants. In addition to increasing ECD and DCD utilization, increasing use of deceased donors with certain types of infections such as Hepatitis B and C, and increasing use of living donor liver, lung and intestinal transplants may also augment the organ supply. The extent by which donors may be offered incentives for donation, and the practical, ethical and legal implications of compensating organ donors were also debated. The expanded use of nonstandard organs raises potential ethical considerations about appropriate recipient selection, informed consent and concerns that the current regulatory environment discourages and penalizes these efforts.",
keywords = "Access to transplantation, Deceased donor kidneys, Deceased donor organs, Donor/recipient matching, Ethics, Expanded criteria donors, Live donor transplantation, Organ donation, Organ sales, Organ shortage",
author = "Pomfret, {E. A.} and Sung, {R. S.} and J. Allan and Milan Kinkhabwala and Melancon, {J. K.} and Roberts, {J. P.}",
year = "2008",
month = "4",
doi = "10.1111/j.1600-6143.2007.02146.x",
language = "English (US)",
volume = "8",
pages = "745--752",
journal = "American Journal of Transplantation",
issn = "1600-6135",
publisher = "Wiley-Blackwell",
number = "4",

}

TY - JOUR

T1 - Solving the organ shortage crisis

T2 - The 7th Annual American Society of Transplant Surgeons' State-of-the-Art Winter Symposium

AU - Pomfret, E. A.

AU - Sung, R. S.

AU - Allan, J.

AU - Kinkhabwala, Milan

AU - Melancon, J. K.

AU - Roberts, J. P.

PY - 2008/4

Y1 - 2008/4

N2 - The 2007 American Society of Transplant Surgeons' (ASTS) State-of-the-Art Winter Symposium entitled, 'Solving the Organ Shortage Crisis' explored ways to increase the supply of donor organs to meet the challenge of increasing waiting lists and deaths while awaiting transplantation. While the increasing use of organs previously considered marginal, such as those from expanded criteria donors (ECD) or donors after cardiac death (DCD) has increased the number of transplants from deceased donors, these transplants are often associated with inferior outcomes and higher costs. The need remains for innovative ways to increase both deceased and living donor transplants. In addition to increasing ECD and DCD utilization, increasing use of deceased donors with certain types of infections such as Hepatitis B and C, and increasing use of living donor liver, lung and intestinal transplants may also augment the organ supply. The extent by which donors may be offered incentives for donation, and the practical, ethical and legal implications of compensating organ donors were also debated. The expanded use of nonstandard organs raises potential ethical considerations about appropriate recipient selection, informed consent and concerns that the current regulatory environment discourages and penalizes these efforts.

AB - The 2007 American Society of Transplant Surgeons' (ASTS) State-of-the-Art Winter Symposium entitled, 'Solving the Organ Shortage Crisis' explored ways to increase the supply of donor organs to meet the challenge of increasing waiting lists and deaths while awaiting transplantation. While the increasing use of organs previously considered marginal, such as those from expanded criteria donors (ECD) or donors after cardiac death (DCD) has increased the number of transplants from deceased donors, these transplants are often associated with inferior outcomes and higher costs. The need remains for innovative ways to increase both deceased and living donor transplants. In addition to increasing ECD and DCD utilization, increasing use of deceased donors with certain types of infections such as Hepatitis B and C, and increasing use of living donor liver, lung and intestinal transplants may also augment the organ supply. The extent by which donors may be offered incentives for donation, and the practical, ethical and legal implications of compensating organ donors were also debated. The expanded use of nonstandard organs raises potential ethical considerations about appropriate recipient selection, informed consent and concerns that the current regulatory environment discourages and penalizes these efforts.

KW - Access to transplantation

KW - Deceased donor kidneys

KW - Deceased donor organs

KW - Donor/recipient matching

KW - Ethics

KW - Expanded criteria donors

KW - Live donor transplantation

KW - Organ donation

KW - Organ sales

KW - Organ shortage

UR - http://www.scopus.com/inward/record.url?scp=40449114529&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=40449114529&partnerID=8YFLogxK

U2 - 10.1111/j.1600-6143.2007.02146.x

DO - 10.1111/j.1600-6143.2007.02146.x

M3 - Article

VL - 8

SP - 745

EP - 752

JO - American Journal of Transplantation

JF - American Journal of Transplantation

SN - 1600-6135

IS - 4

ER -