Solvent-controlled Csp2→O silyl migration: The "one-pot" synthesis of 2,3-disubsituted thiophenes

Nelmi O. Devarie-Baez, Brian J. Shuhler, Hua Wang, Ming Xian

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Abstract

(Chemical Equation Presented) An effective "one-pot" synthesis of disubstituted thiophene derivatives employing 3-bromo-2-silyl thiophenes has been developed. A solvent-controlled [1,4] Csp2→O silyl migration was involved as the key step in this process.

Original languageEnglish (US)
Pages (from-to)4655-4658
Number of pages4
JournalOrganic Letters
Volume9
Issue number22
DOIs
Publication statusPublished - Oct 25 2007

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ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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