Sodium polystyrene sulfonate (SPS): Sorbitol-induced colonic necrosis

Mohamad Erfani, Yougandhar Akula, Touraj Zolfaghari, Hilary I. Hertan

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Sodium polystyrene sulfonate (SPS) is a cation exchange resin which primarily acts in the colon. It is usually administered with an osmotic laxative (e.g. sorbitol), orally or as a retention enema, to treat hyperkalemia. SPS-sorbitol use has been implicated in damage to different parts of the gastrointestinal (GI) tract. Adverse GI reactions include anorexia, nausea, vomiting, constipation, fecal impaction, intestinal obstruction and intestinal necrosis (rare). We present an uncommon case of ulceration with necrosis of the ascending colon following multiple oral SPS-sorbitol administrations.

Original languageEnglish (US)
Pages (from-to)47-50
Number of pages4
JournalPractical Gastroenterology
Volume34
Issue number11
StatePublished - Nov 2010

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Sorbitol
Necrosis
Fecal Impaction
Cation Exchange Resins
Ascending Colon
Laxatives
Hyperkalemia
Intestinal Obstruction
Enema
Anorexia
Constipation
Nausea
Vomiting
Gastrointestinal Tract
Colon
polystyrene sulfonic acid

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Sodium polystyrene sulfonate (SPS) : Sorbitol-induced colonic necrosis. / Erfani, Mohamad; Akula, Yougandhar; Zolfaghari, Touraj; Hertan, Hilary I.

In: Practical Gastroenterology, Vol. 34, No. 11, 11.2010, p. 47-50.

Research output: Contribution to journalArticle

Erfani, M, Akula, Y, Zolfaghari, T & Hertan, HI 2010, 'Sodium polystyrene sulfonate (SPS): Sorbitol-induced colonic necrosis', Practical Gastroenterology, vol. 34, no. 11, pp. 47-50.
Erfani, Mohamad ; Akula, Yougandhar ; Zolfaghari, Touraj ; Hertan, Hilary I. / Sodium polystyrene sulfonate (SPS) : Sorbitol-induced colonic necrosis. In: Practical Gastroenterology. 2010 ; Vol. 34, No. 11. pp. 47-50.
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