Socio-demographic and clinical characterization of patients with obsessive-compulsive tic-related disorder (OCTD): An Italian multicenter study

B. Dell'Osso, B. Benatti, Eric Hollander, J. Zohar, L. Dell'Osso, N. A. Fineberg, M. Marcatili, S. Rigardetto, M. Briguglio, D. Marazziti, F. Mucci, O. Gambini, A. Tundo, R. Necci, D. De Berardis, R. Galentino, S. De Michele, C. D'Addario, D. Servello, U. AlbertG. Maina, D. De Ronchi, A. C. Altamura, M. Porta

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In the DSM-5 a new "tic-related" specifier for obsessive compulsive disorder (OCD) has been introduced, highlighting the importance of an accurate characterization of patients suffering from obsessive-compulsive tic-related disorder ("OCTD"). In order to characterize OCTD from a socio-demographic and clinical perspective, the present multicenter study was carried out. The sample consists of 266 patients, divided in two groups with lifetime diagnoses of OCD and OCTD, respectively. OCTD vs OCD patients showed a significant male prevalence (68.5% vs 48.5%; p < .001), a higher rate of psychiatric comorbidities (69.4 vs 50%; p < .001) - mainly with neurodevelopmental disorders (24 vs 0%; p < .001), a lower education level and professional status (middle school diploma: 25 vs 7.6%; full-Time job 44.4 vs 58%; p < .001). Moreover, OCTD vs OCD patients showed significantly earlier age of OCD and psychiatric comorbidity onsets (16.1 ± 10.8 vs 22.1 ± 9.5 years; p < .001, and 18.3 ± 12.8 vs 25.6 ± 9.4: p < .001, respectively). Patients with OCTD patients were treated mainly with antipsychotic and with a low rate of benzodiazepine (74.2 vs 38.2% and 20.2 vs 31.3%, respectively; p < .001). Finally, OCTD vs OCD patients showed higher rates of partial treatment response (58.1 vs 38%; p < .001), lower rates of current remission (35.5 vs 54.8%; p < .001) and higher rates of suicidal ideation (63.2 vs 41.7%; p < .001) and attempts (28.9 vs 8.3%; p < .001). Patients with OCTD report several unfavorable socio-demographic and clinical characteristics compared to OCD patients without a history of tic. Additional studies on larger sample are needed to further characterize OCTD patients from clinical and therapeutic perspectives.

Original languageEnglish (US)
Pages (from-to)148-153
Number of pages6
JournalJournal of Psychopathology
Volume24
Issue number3
StatePublished - Sep 1 2018

Fingerprint

Tic Disorders
Multicenter Studies
Obsessive-Compulsive Disorder
Demography
Tics
Psychiatry
Comorbidity
Suicidal Ideation
Professional Education
Benzodiazepines
Antipsychotic Agents

Keywords

  • Obsessive-Compulsive Disorder
  • Obsessive-Compulsive Tic Disorder
  • Tic Disorder

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health

Cite this

Socio-demographic and clinical characterization of patients with obsessive-compulsive tic-related disorder (OCTD) : An Italian multicenter study. / Dell'Osso, B.; Benatti, B.; Hollander, Eric; Zohar, J.; Dell'Osso, L.; Fineberg, N. A.; Marcatili, M.; Rigardetto, S.; Briguglio, M.; Marazziti, D.; Mucci, F.; Gambini, O.; Tundo, A.; Necci, R.; De Berardis, D.; Galentino, R.; De Michele, S.; D'Addario, C.; Servello, D.; Albert, U.; Maina, G.; De Ronchi, D.; Altamura, A. C.; Porta, M.

In: Journal of Psychopathology, Vol. 24, No. 3, 01.09.2018, p. 148-153.

Research output: Contribution to journalArticle

Dell'Osso, B, Benatti, B, Hollander, E, Zohar, J, Dell'Osso, L, Fineberg, NA, Marcatili, M, Rigardetto, S, Briguglio, M, Marazziti, D, Mucci, F, Gambini, O, Tundo, A, Necci, R, De Berardis, D, Galentino, R, De Michele, S, D'Addario, C, Servello, D, Albert, U, Maina, G, De Ronchi, D, Altamura, AC & Porta, M 2018, 'Socio-demographic and clinical characterization of patients with obsessive-compulsive tic-related disorder (OCTD): An Italian multicenter study', Journal of Psychopathology, vol. 24, no. 3, pp. 148-153.
Dell'Osso, B. ; Benatti, B. ; Hollander, Eric ; Zohar, J. ; Dell'Osso, L. ; Fineberg, N. A. ; Marcatili, M. ; Rigardetto, S. ; Briguglio, M. ; Marazziti, D. ; Mucci, F. ; Gambini, O. ; Tundo, A. ; Necci, R. ; De Berardis, D. ; Galentino, R. ; De Michele, S. ; D'Addario, C. ; Servello, D. ; Albert, U. ; Maina, G. ; De Ronchi, D. ; Altamura, A. C. ; Porta, M. / Socio-demographic and clinical characterization of patients with obsessive-compulsive tic-related disorder (OCTD) : An Italian multicenter study. In: Journal of Psychopathology. 2018 ; Vol. 24, No. 3. pp. 148-153.
@article{66e26ba91a2849b6a89c0d4becadde17,
title = "Socio-demographic and clinical characterization of patients with obsessive-compulsive tic-related disorder (OCTD): An Italian multicenter study",
abstract = "In the DSM-5 a new {"}tic-related{"} specifier for obsessive compulsive disorder (OCD) has been introduced, highlighting the importance of an accurate characterization of patients suffering from obsessive-compulsive tic-related disorder ({"}OCTD{"}). In order to characterize OCTD from a socio-demographic and clinical perspective, the present multicenter study was carried out. The sample consists of 266 patients, divided in two groups with lifetime diagnoses of OCD and OCTD, respectively. OCTD vs OCD patients showed a significant male prevalence (68.5{\%} vs 48.5{\%}; p < .001), a higher rate of psychiatric comorbidities (69.4 vs 50{\%}; p < .001) - mainly with neurodevelopmental disorders (24 vs 0{\%}; p < .001), a lower education level and professional status (middle school diploma: 25 vs 7.6{\%}; full-Time job 44.4 vs 58{\%}; p < .001). Moreover, OCTD vs OCD patients showed significantly earlier age of OCD and psychiatric comorbidity onsets (16.1 ± 10.8 vs 22.1 ± 9.5 years; p < .001, and 18.3 ± 12.8 vs 25.6 ± 9.4: p < .001, respectively). Patients with OCTD patients were treated mainly with antipsychotic and with a low rate of benzodiazepine (74.2 vs 38.2{\%} and 20.2 vs 31.3{\%}, respectively; p < .001). Finally, OCTD vs OCD patients showed higher rates of partial treatment response (58.1 vs 38{\%}; p < .001), lower rates of current remission (35.5 vs 54.8{\%}; p < .001) and higher rates of suicidal ideation (63.2 vs 41.7{\%}; p < .001) and attempts (28.9 vs 8.3{\%}; p < .001). Patients with OCTD report several unfavorable socio-demographic and clinical characteristics compared to OCD patients without a history of tic. Additional studies on larger sample are needed to further characterize OCTD patients from clinical and therapeutic perspectives.",
keywords = "Obsessive-Compulsive Disorder, Obsessive-Compulsive Tic Disorder, Tic Disorder",
author = "B. Dell'Osso and B. Benatti and Eric Hollander and J. Zohar and L. Dell'Osso and Fineberg, {N. A.} and M. Marcatili and S. Rigardetto and M. Briguglio and D. Marazziti and F. Mucci and O. Gambini and A. Tundo and R. Necci and {De Berardis}, D. and R. Galentino and {De Michele}, S. and C. D'Addario and D. Servello and U. Albert and G. Maina and {De Ronchi}, D. and Altamura, {A. C.} and M. Porta",
year = "2018",
month = "9",
day = "1",
language = "English (US)",
volume = "24",
pages = "148--153",
journal = "Giornale Italiano di Psicopatologia",
issn = "1592-1107",
publisher = "Pacini Editore s.r.l.",
number = "3",

}

TY - JOUR

T1 - Socio-demographic and clinical characterization of patients with obsessive-compulsive tic-related disorder (OCTD)

T2 - An Italian multicenter study

AU - Dell'Osso, B.

AU - Benatti, B.

AU - Hollander, Eric

AU - Zohar, J.

AU - Dell'Osso, L.

AU - Fineberg, N. A.

AU - Marcatili, M.

AU - Rigardetto, S.

AU - Briguglio, M.

AU - Marazziti, D.

AU - Mucci, F.

AU - Gambini, O.

AU - Tundo, A.

AU - Necci, R.

AU - De Berardis, D.

AU - Galentino, R.

AU - De Michele, S.

AU - D'Addario, C.

AU - Servello, D.

AU - Albert, U.

AU - Maina, G.

AU - De Ronchi, D.

AU - Altamura, A. C.

AU - Porta, M.

PY - 2018/9/1

Y1 - 2018/9/1

N2 - In the DSM-5 a new "tic-related" specifier for obsessive compulsive disorder (OCD) has been introduced, highlighting the importance of an accurate characterization of patients suffering from obsessive-compulsive tic-related disorder ("OCTD"). In order to characterize OCTD from a socio-demographic and clinical perspective, the present multicenter study was carried out. The sample consists of 266 patients, divided in two groups with lifetime diagnoses of OCD and OCTD, respectively. OCTD vs OCD patients showed a significant male prevalence (68.5% vs 48.5%; p < .001), a higher rate of psychiatric comorbidities (69.4 vs 50%; p < .001) - mainly with neurodevelopmental disorders (24 vs 0%; p < .001), a lower education level and professional status (middle school diploma: 25 vs 7.6%; full-Time job 44.4 vs 58%; p < .001). Moreover, OCTD vs OCD patients showed significantly earlier age of OCD and psychiatric comorbidity onsets (16.1 ± 10.8 vs 22.1 ± 9.5 years; p < .001, and 18.3 ± 12.8 vs 25.6 ± 9.4: p < .001, respectively). Patients with OCTD patients were treated mainly with antipsychotic and with a low rate of benzodiazepine (74.2 vs 38.2% and 20.2 vs 31.3%, respectively; p < .001). Finally, OCTD vs OCD patients showed higher rates of partial treatment response (58.1 vs 38%; p < .001), lower rates of current remission (35.5 vs 54.8%; p < .001) and higher rates of suicidal ideation (63.2 vs 41.7%; p < .001) and attempts (28.9 vs 8.3%; p < .001). Patients with OCTD report several unfavorable socio-demographic and clinical characteristics compared to OCD patients without a history of tic. Additional studies on larger sample are needed to further characterize OCTD patients from clinical and therapeutic perspectives.

AB - In the DSM-5 a new "tic-related" specifier for obsessive compulsive disorder (OCD) has been introduced, highlighting the importance of an accurate characterization of patients suffering from obsessive-compulsive tic-related disorder ("OCTD"). In order to characterize OCTD from a socio-demographic and clinical perspective, the present multicenter study was carried out. The sample consists of 266 patients, divided in two groups with lifetime diagnoses of OCD and OCTD, respectively. OCTD vs OCD patients showed a significant male prevalence (68.5% vs 48.5%; p < .001), a higher rate of psychiatric comorbidities (69.4 vs 50%; p < .001) - mainly with neurodevelopmental disorders (24 vs 0%; p < .001), a lower education level and professional status (middle school diploma: 25 vs 7.6%; full-Time job 44.4 vs 58%; p < .001). Moreover, OCTD vs OCD patients showed significantly earlier age of OCD and psychiatric comorbidity onsets (16.1 ± 10.8 vs 22.1 ± 9.5 years; p < .001, and 18.3 ± 12.8 vs 25.6 ± 9.4: p < .001, respectively). Patients with OCTD patients were treated mainly with antipsychotic and with a low rate of benzodiazepine (74.2 vs 38.2% and 20.2 vs 31.3%, respectively; p < .001). Finally, OCTD vs OCD patients showed higher rates of partial treatment response (58.1 vs 38%; p < .001), lower rates of current remission (35.5 vs 54.8%; p < .001) and higher rates of suicidal ideation (63.2 vs 41.7%; p < .001) and attempts (28.9 vs 8.3%; p < .001). Patients with OCTD report several unfavorable socio-demographic and clinical characteristics compared to OCD patients without a history of tic. Additional studies on larger sample are needed to further characterize OCTD patients from clinical and therapeutic perspectives.

KW - Obsessive-Compulsive Disorder

KW - Obsessive-Compulsive Tic Disorder

KW - Tic Disorder

UR - http://www.scopus.com/inward/record.url?scp=85054569868&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85054569868&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:85054569868

VL - 24

SP - 148

EP - 153

JO - Giornale Italiano di Psicopatologia

JF - Giornale Italiano di Psicopatologia

SN - 1592-1107

IS - 3

ER -