Sleep‐induced nonobstructive hypoventilation associated with diaphragmatic paralysis

Michael J. Thorpy; Wolfgang W. Schmidt‐Nowara; Charles P. Pollak; Elliot D. Weitzman

doi:10.1002/ana.410120318

Sleep‐induced nonobstructive hypoventilation associated with diaphragmatic paralysis

Michael J. Thorpy, Wolfgang W. Schmidt‐Nowara, Charles P. Pollak, Elliot D. Weitzman

Neurology

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

A patient with adult‐onset spinal muscular atrophy causing mild proximal limb muscle weakness had sleep‐induced nonobstructive hypoventilation due to diaphragmatic paralysis. Nocturnal dyspnea and daytime somnolence were associated with frequent arousals from sleep due to arterial oxygen desaturation. The nocturnal use of a cuirass respirator improved the oxygen saturation, resulting in less disrupted sleep, relief of the somnolence, and improved daytime ventilation.

Original language	English (US)
Pages (from-to)	308-311
Number of pages	4
Journal	Annals of Neurology
Volume	12
Issue number	3
DOIs	https://doi.org/10.1002/ana.410120318
State	Published - Sep 1982

ASJC Scopus subject areas

Neurology
Clinical Neurology

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abstract = "A patient with adult‐onset spinal muscular atrophy causing mild proximal limb muscle weakness had sleep‐induced nonobstructive hypoventilation due to diaphragmatic paralysis. Nocturnal dyspnea and daytime somnolence were associated with frequent arousals from sleep due to arterial oxygen desaturation. The nocturnal use of a cuirass respirator improved the oxygen saturation, resulting in less disrupted sleep, relief of the somnolence, and improved daytime ventilation.",

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AU - Thorpy, Michael J.

AU - Schmidt‐Nowara, Wolfgang W.

AU - Pollak, Charles P.

AU - Weitzman, Elliot D.

PY - 1982/9

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N2 - A patient with adult‐onset spinal muscular atrophy causing mild proximal limb muscle weakness had sleep‐induced nonobstructive hypoventilation due to diaphragmatic paralysis. Nocturnal dyspnea and daytime somnolence were associated with frequent arousals from sleep due to arterial oxygen desaturation. The nocturnal use of a cuirass respirator improved the oxygen saturation, resulting in less disrupted sleep, relief of the somnolence, and improved daytime ventilation.

AB - A patient with adult‐onset spinal muscular atrophy causing mild proximal limb muscle weakness had sleep‐induced nonobstructive hypoventilation due to diaphragmatic paralysis. Nocturnal dyspnea and daytime somnolence were associated with frequent arousals from sleep due to arterial oxygen desaturation. The nocturnal use of a cuirass respirator improved the oxygen saturation, resulting in less disrupted sleep, relief of the somnolence, and improved daytime ventilation.

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Sleep‐induced nonobstructive hypoventilation associated with diaphragmatic paralysis

Abstract

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