Sleep-induced nonobstructive hypoventilation associated with diaphragmatic paralysis

Michael J. Thorpy, W. W. Schmidt-Nowara, C. P. Pollak, E. D. Weitzman

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

A patient with adult-onset spinal muscular atrophy causing mild proximal limb muscle weakness had sleep-induced nonobstructive hypoventilation due to diaphragmatic paralysis. Nocturnal dyspnea and daytime somnolence were associated with frequent arousals from sleep due to arterial oxygen desaturation. The nocturnal use of a cuirass respirator improved the oxygen saturation, resulting in less disrupted sleep, relief of the somnolence, and improved daytime ventilation.

Original languageEnglish (US)
Pages (from-to)308-311
Number of pages4
JournalAnnals of Neurology
Volume12
Issue number3
StatePublished - 1982

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Respiratory Paralysis
Hypoventilation
Sleep
Oxygen
Spinal Muscular Atrophy
Muscle Weakness
Mechanical Ventilators
Arousal
Dyspnea
Ventilation
Extremities

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Thorpy, M. J., Schmidt-Nowara, W. W., Pollak, C. P., & Weitzman, E. D. (1982). Sleep-induced nonobstructive hypoventilation associated with diaphragmatic paralysis. Annals of Neurology, 12(3), 308-311.

Sleep-induced nonobstructive hypoventilation associated with diaphragmatic paralysis. / Thorpy, Michael J.; Schmidt-Nowara, W. W.; Pollak, C. P.; Weitzman, E. D.

In: Annals of Neurology, Vol. 12, No. 3, 1982, p. 308-311.

Research output: Contribution to journalArticle

Thorpy, MJ, Schmidt-Nowara, WW, Pollak, CP & Weitzman, ED 1982, 'Sleep-induced nonobstructive hypoventilation associated with diaphragmatic paralysis', Annals of Neurology, vol. 12, no. 3, pp. 308-311.
Thorpy, Michael J. ; Schmidt-Nowara, W. W. ; Pollak, C. P. ; Weitzman, E. D. / Sleep-induced nonobstructive hypoventilation associated with diaphragmatic paralysis. In: Annals of Neurology. 1982 ; Vol. 12, No. 3. pp. 308-311.
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