Skin Metabolite, Farnesyl Pyrophosphate, Regulates Epidermal Response to Inflammation, Oxidative Stress, and Migration

Medicine & Life Sciences

• farnesyl pyrophosphate 100%
• Oxidative Stress 47%
• Inflammation 37%
• Skin 35%
• Glucocorticoids 14%
• Glucocorticoid Receptors 11%
• Keratinocytes 10%
• Interferons 9%
• Keratin-6 9%
• Farnesyl-Diphosphate Farnesyltransferase 9%
• Genes 8%
• Squalene 7%
• Cholesterol 7%
• Down-Regulation 7%
• Mevalonic Acid 7%
• Adherens Junctions 6%
• Co-Repressor Proteins 6%
• Catenins 6%
• Terpenes 6%
• Sterols 6%
• Chromatin Immunoprecipitation 5%
• Microarray Analysis 5%
• Epidermis 5%
• Hydroxymethylglutaryl-CoA Reductase Inhibitors 5%
• Immunoprecipitation 5%
• Lipid Metabolism 5%
• Transfection 4%
• Immunosuppressive Agents 4%
• Intercellular Signaling Peptides and Proteins 4%
• Acids 4%
• Homeostasis 3%
• Ligands 3%
• Insulin 3%
• In Vitro Techniques 2%
• Therapeutics 1%

Chemical Compounds

• Glucocorticoid 82%
• Oxidative Stress 63%
• Metabolite 45%
• Cholesterol 23%
• EC 2.5.1.21 (Squalene Synthase) Inhibitor 22%
• Hydroxymethylglutaryl Coenzyme A Reductase Inhibitor 18%
• Mevalonate 18%
• Cytoprotective 17%
• Squalene 16%
• Isoprenoid 16%
• Growth Factor 15%
• Sterol 14%
• Microarrays 13%
• Insulin Derivative 13%
• Pharmacological Metabolism 9%
• Lipid 8%
• Block Like Crystal 8%
• Ligand 5%
• Acid 4%