Skin closure with dye-enhanced laser welding and fibrinogen

Todd M. Wider, Steven K. Libutti, Daniel P. Greenwald, Mehmet C. Oz, Jeffrey S. Yager, Michael R. Treat, Norman E. Hugo

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Initial studies of laser welding for skin closure in mouse models demonstrated that while bursting strength was not compromised, the levels of collagen-specific messenger ribonucleic acid were significantly lower when compared to the control group of simple suture closure. A superior cosmetic result of the laser welded incisions was also claimed. Recently, the topical application of wavelength specific dyes has been used to enhance laser closure for vascular anastomoses. Laser welding offers many possible advantages over suture closure including shorter operative time, decreased foreign body reaction, and possibly decreased scar formation. We compared the in vivo closure of cutaneous incisions welded with argon laser/fluorescein isothiocyanate dye (FITC)/fibrinogen, and diode laser/indocyanine green dye (ICG)/fibrinogen, to closure by simple suture.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsOon T. Tan, Rodney A. White, John V. White
PublisherPubl by Int Soc for Optical Engineering
Pages56-61
Number of pages6
Volume1422
StatePublished - 1991
Externally publishedYes
EventProceedings of Lasers in Dermatology and Tissue Weldings - Los Angeles, CA, USA
Duration: Jan 21 1991Jan 22 1991

Other

OtherProceedings of Lasers in Dermatology and Tissue Weldings
CityLos Angeles, CA, USA
Period1/21/911/22/91

Fingerprint

fibrinogen
laser welding
Laser beam welding
closures
Skin
Dyes
dyes
Argon lasers
Dye lasers
Lasers
RNA
Collagen
Semiconductor lasers
Wavelength
foreign bodies
ribonucleic acids
argon lasers
scars
collagens
lasers

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Wider, T. M., Libutti, S. K., Greenwald, D. P., Oz, M. C., Yager, J. S., Treat, M. R., & Hugo, N. E. (1991). Skin closure with dye-enhanced laser welding and fibrinogen. In O. T. Tan, R. A. White, & J. V. White (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 1422, pp. 56-61). Publ by Int Soc for Optical Engineering.

Skin closure with dye-enhanced laser welding and fibrinogen. / Wider, Todd M.; Libutti, Steven K.; Greenwald, Daniel P.; Oz, Mehmet C.; Yager, Jeffrey S.; Treat, Michael R.; Hugo, Norman E.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / Oon T. Tan; Rodney A. White; John V. White. Vol. 1422 Publ by Int Soc for Optical Engineering, 1991. p. 56-61.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Wider, TM, Libutti, SK, Greenwald, DP, Oz, MC, Yager, JS, Treat, MR & Hugo, NE 1991, Skin closure with dye-enhanced laser welding and fibrinogen. in OT Tan, RA White & JV White (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 1422, Publ by Int Soc for Optical Engineering, pp. 56-61, Proceedings of Lasers in Dermatology and Tissue Weldings, Los Angeles, CA, USA, 1/21/91.
Wider TM, Libutti SK, Greenwald DP, Oz MC, Yager JS, Treat MR et al. Skin closure with dye-enhanced laser welding and fibrinogen. In Tan OT, White RA, White JV, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 1422. Publ by Int Soc for Optical Engineering. 1991. p. 56-61
Wider, Todd M. ; Libutti, Steven K. ; Greenwald, Daniel P. ; Oz, Mehmet C. ; Yager, Jeffrey S. ; Treat, Michael R. ; Hugo, Norman E. / Skin closure with dye-enhanced laser welding and fibrinogen. Proceedings of SPIE - The International Society for Optical Engineering. editor / Oon T. Tan ; Rodney A. White ; John V. White. Vol. 1422 Publ by Int Soc for Optical Engineering, 1991. pp. 56-61
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abstract = "Initial studies of laser welding for skin closure in mouse models demonstrated that while bursting strength was not compromised, the levels of collagen-specific messenger ribonucleic acid were significantly lower when compared to the control group of simple suture closure. A superior cosmetic result of the laser welded incisions was also claimed. Recently, the topical application of wavelength specific dyes has been used to enhance laser closure for vascular anastomoses. Laser welding offers many possible advantages over suture closure including shorter operative time, decreased foreign body reaction, and possibly decreased scar formation. We compared the in vivo closure of cutaneous incisions welded with argon laser/fluorescein isothiocyanate dye (FITC)/fibrinogen, and diode laser/indocyanine green dye (ICG)/fibrinogen, to closure by simple suture.",
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