SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species

Xiao Tian; Denis Firsanov; Zhihui Zhang; Yang Cheng; Lingfeng Luo; Gregory Tombline; Ruiyue Tan; Matthew Simon; Steven Henderson; Janine Steffan; Audrey Goldfarb; Jonathan Tam; Kitty Zheng; Adam Cornwell; Adam Johnson; Jiang Nan Yang; Zhiyong Mao; Bruno Manta; Weiwei Dang; Zhengdong Zhang; Jan Vijg; Aaron Wolfe; Kelsey Moody; Brian K. Kennedy; Dirk Bohmann; Vadim N. Gladyshev; Andrei Seluanov; Vera Gorbunova

doi:10.1016/j.cell.2019.03.043

SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species

Xiao Tian, Denis Firsanov, Zhihui Zhang, Yang Cheng, Lingfeng Luo, Gregory Tombline, Ruiyue Tan, Matthew Simon, Steven Henderson, Janine Steffan, Audrey Goldfarb, Jonathan Tam, Kitty Zheng, Adam Cornwell, Adam Johnson, Jiang Nan Yang, Zhiyong Mao, Bruno Manta, Weiwei Dang, Zhengdong ZhangJan Vijg, Aaron Wolfe, Kelsey Moody, Brian K. Kennedy, Dirk Bohmann, Vadim N. Gladyshev, Andrei Seluanov, Vera Gorbunova

Genetics

Research output: Contribution to journal › Article › peer-review

188 Scopus citations

Abstract

A

Original language	English (US)
Pages (from-to)	622-638.e22
Journal	Cell
Volume	177
Issue number	3
DOIs	https://doi.org/10.1016/j.cell.2019.03.043
State	Published - Apr 18 2019

Keywords

DNA DSB repair
DNA repair
NER
SIRT6
aging
longevity

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2019.03.043

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Tian, X., Firsanov, D., Zhang, Z., Cheng, Y., Luo, L., Tombline, G., Tan, R., Simon, M., Henderson, S., Steffan, J., Goldfarb, A., Tam, J., Zheng, K., Cornwell, A., Johnson, A., Yang, J. N., Mao, Z., Manta, B., Dang, W., ... Gorbunova, V. (2019). SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species. Cell, 177(3), 622-638.e22. https://doi.org/10.1016/j.cell.2019.03.043

Tian, X, Firsanov, D, Zhang, Z, Cheng, Y, Luo, L, Tombline, G, Tan, R, Simon, M, Henderson, S, Steffan, J, Goldfarb, A, Tam, J, Zheng, K, Cornwell, A, Johnson, A, Yang, JN, Mao, Z, Manta, B, Dang, W, Zhang, Z , Vijg, J, Wolfe, A, Moody, K, Kennedy, BK, Bohmann, D, Gladyshev, VN, Seluanov, A & Gorbunova, V 2019, 'SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species', Cell, vol. 177, no. 3, pp. 622-638.e22. https://doi.org/10.1016/j.cell.2019.03.043

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title = "SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species",

abstract = "A",

keywords = "DNA DSB repair, DNA repair, NER, SIRT6, aging, longevity",

author = "Xiao Tian and Denis Firsanov and Zhihui Zhang and Yang Cheng and Lingfeng Luo and Gregory Tombline and Ruiyue Tan and Matthew Simon and Steven Henderson and Janine Steffan and Audrey Goldfarb and Jonathan Tam and Kitty Zheng and Adam Cornwell and Adam Johnson and Yang, {Jiang Nan} and Zhiyong Mao and Bruno Manta and Weiwei Dang and Zhengdong Zhang and Jan Vijg and Aaron Wolfe and Kelsey Moody and Kennedy, {Brian K.} and Dirk Bohmann and Gladyshev, {Vadim N.} and Andrei Seluanov and Vera Gorbunova",

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year = "2019",

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day = "18",

doi = "10.1016/j.cell.2019.03.043",

language = "English (US)",

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T1 - SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species

AU - Tian, Xiao

AU - Firsanov, Denis

AU - Zhang, Zhihui

AU - Cheng, Yang

AU - Luo, Lingfeng

AU - Tombline, Gregory

AU - Tan, Ruiyue

AU - Simon, Matthew

AU - Henderson, Steven

AU - Steffan, Janine

AU - Goldfarb, Audrey

AU - Tam, Jonathan

AU - Zheng, Kitty

AU - Cornwell, Adam

AU - Johnson, Adam

AU - Yang, Jiang Nan

AU - Mao, Zhiyong

AU - Manta, Bruno

AU - Dang, Weiwei

AU - Zhang, Zhengdong

AU - Vijg, Jan

AU - Wolfe, Aaron

AU - Moody, Kelsey

AU - Kennedy, Brian K.

AU - Bohmann, Dirk

AU - Gladyshev, Vadim N.

AU - Seluanov, Andrei

AU - Gorbunova, Vera

PY - 2019/4/18

Y1 - 2019/4/18

N2 - A

AB - A

KW - DNA DSB repair

KW - DNA repair

KW - NER

KW - SIRT6

KW - aging

KW - longevity

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ER -

SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species

Abstract

Keywords

ASJC Scopus subject areas

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