The simulation of proton Spread-Out Bragg Peaks (SOBPs) was implemented using the Geant4-based TOPAS Monte Carlo software. Dynamic proton energy switching was implemented using TOPAS time features, while beam weights were calculated using an empirical power law formalism with Bragg peaks spaced by 0.5 mm. To find power parameters yielding flat SOBPs we sampled power parameters for maximum kinetic energies of 50 MeV to 250 MeV and SOBP widths of 15% to 40% of the depth of the distal SOBP end. Simulations were run in a 50 cm cubic water phantom using a uniform squared proton beam. Depth dose was scored along the central axis in a binned cylinder with 1 cm diameter in 2.5 mm increments. Power parameters yielding a flat SOBPs were found to vary with, both energy and SOBP width and differed significantly from previously reported values based on simulations with MCNPX.
- proton therapy
ASJC Scopus subject areas