Silent corticotroph adenoma with multiple cysts

Pars intermedia tumor?

Hiroshi Nishioka, Asao Hirano, Sylvia L. Asa

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A silent corticotroph adenoma with multiple cysts was found incidentally at autopsy. By immunohistochemistry, most of the adenoma cells contained reactivity for adrenocorticotropic hormone and beta-endorphin; a few cells stained for beta-subunit of luteinizing hormone. The cysts, interspersed within the tumor, were lined by cuboidal epithelium with foci of stratified squamous epithelium. The lining cells contained immunoreactive keratin; some cells were positive for S-100 protein or glial fibrillary acidic protein, and a few cells were also immuno-stained for adrenocorticotropic hormone and beta-endorphin. It is suggested that this tumor may represent a neoplasm of pars intermedia derivation.

Original languageEnglish (US)
Pages (from-to)47-51
Number of pages5
JournalEndocrine Pathology
Volume3
Issue number1
DOIs
StatePublished - Mar 1992

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ACTH-Secreting Pituitary Adenoma
Cysts
beta-Endorphin
Neoplasms
Adrenocorticotropic Hormone
Epithelium
Beta Subunit Luteinizing Hormone
S100 Proteins
Glial Fibrillary Acidic Protein
Keratins
Adenoma
Autopsy
Immunohistochemistry

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Silent corticotroph adenoma with multiple cysts : Pars intermedia tumor? / Nishioka, Hiroshi; Hirano, Asao; Asa, Sylvia L.

In: Endocrine Pathology, Vol. 3, No. 1, 03.1992, p. 47-51.

Research output: Contribution to journalArticle

Nishioka, Hiroshi ; Hirano, Asao ; Asa, Sylvia L. / Silent corticotroph adenoma with multiple cysts : Pars intermedia tumor?. In: Endocrine Pathology. 1992 ; Vol. 3, No. 1. pp. 47-51.
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