Short report

Protein kinase A regulatory subunit interacts with P-type ATPases in Trypanosoma cruzi

Yi Bao, Louis M. Weiss, Muneaki Hashimoto, Takeshi Nara, Huan Huang

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Cyclic AMP-protein kinase A (PKA) signaling is important for the growth and differentiation of Trypanosoma cruzi. Immunofluorescence suggests that PKA can associate with the plasma membrane of trypomastigotes. We found that the PKA regulatory subunit interacts with several P-type ATPases. These P-type ATPases may play a role in anchoring PKA to the plasma membrane in T. cruzi.

Original languageEnglish (US)
Pages (from-to)941-943
Number of pages3
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume80
Issue number6
StatePublished - Jun 2009

Fingerprint

Trypanosoma cruzi
Cyclic AMP-Dependent Protein Kinases
Adenosine Triphosphatases
Cell Membrane
Adenylate Kinase
Cyclic AMP
Fluorescent Antibody Technique
Growth

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Virology
  • Medicine(all)

Cite this

Short report : Protein kinase A regulatory subunit interacts with P-type ATPases in Trypanosoma cruzi. / Bao, Yi; Weiss, Louis M.; Hashimoto, Muneaki; Nara, Takeshi; Huang, Huan.

In: American Journal of Tropical Medicine and Hygiene, Vol. 80, No. 6, 06.2009, p. 941-943.

Research output: Contribution to journalArticle

@article{eb22e36bc47f4220b5a0c21ff4699a30,
title = "Short report: Protein kinase A regulatory subunit interacts with P-type ATPases in Trypanosoma cruzi",
abstract = "Cyclic AMP-protein kinase A (PKA) signaling is important for the growth and differentiation of Trypanosoma cruzi. Immunofluorescence suggests that PKA can associate with the plasma membrane of trypomastigotes. We found that the PKA regulatory subunit interacts with several P-type ATPases. These P-type ATPases may play a role in anchoring PKA to the plasma membrane in T. cruzi.",
author = "Yi Bao and Weiss, {Louis M.} and Muneaki Hashimoto and Takeshi Nara and Huan Huang",
year = "2009",
month = "6",
language = "English (US)",
volume = "80",
pages = "941--943",
journal = "American Journal of Tropical Medicine and Hygiene",
issn = "0002-9637",
publisher = "American Society of Tropical Medicine and Hygiene",
number = "6",

}

TY - JOUR

T1 - Short report

T2 - Protein kinase A regulatory subunit interacts with P-type ATPases in Trypanosoma cruzi

AU - Bao, Yi

AU - Weiss, Louis M.

AU - Hashimoto, Muneaki

AU - Nara, Takeshi

AU - Huang, Huan

PY - 2009/6

Y1 - 2009/6

N2 - Cyclic AMP-protein kinase A (PKA) signaling is important for the growth and differentiation of Trypanosoma cruzi. Immunofluorescence suggests that PKA can associate with the plasma membrane of trypomastigotes. We found that the PKA regulatory subunit interacts with several P-type ATPases. These P-type ATPases may play a role in anchoring PKA to the plasma membrane in T. cruzi.

AB - Cyclic AMP-protein kinase A (PKA) signaling is important for the growth and differentiation of Trypanosoma cruzi. Immunofluorescence suggests that PKA can associate with the plasma membrane of trypomastigotes. We found that the PKA regulatory subunit interacts with several P-type ATPases. These P-type ATPases may play a role in anchoring PKA to the plasma membrane in T. cruzi.

UR - http://www.scopus.com/inward/record.url?scp=66949143701&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=66949143701&partnerID=8YFLogxK

M3 - Article

VL - 80

SP - 941

EP - 943

JO - American Journal of Tropical Medicine and Hygiene

JF - American Journal of Tropical Medicine and Hygiene

SN - 0002-9637

IS - 6

ER -