Short interpregnancy interval and misoprostol as additive risks for uterine rupture: A case report

Cassandra E. Henderson, Romany Gawargious Hana, Roman Woroch, Kevin D. Reilly

Research output: Contribution to journalArticle

4 Scopus citations


BACKGROUND: Short interpregnancy interval and uterine instrumentation are risk factors for uterine rupture in subsequent pregnancies. Misoprostol as a uterotonic agent is an additive risk factor for rupture of a scarred uterus. CASE: Misoprostol induction for a term stillbirth was complicated by uterine rupture. Risk factors for this uterine rupture might have included interpregnancy intervals of < 7 months, prior uterine instrumentation, and misoprostol as a uterotonic agent. CONCLUSION: Caution and a high index of suspicion are warranted when using misoprostol as a uterotonic agent after a short interpregnancy interval.

Original languageEnglish (US)
Pages (from-to)362-364
Number of pages3
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Issue number7-8
Publication statusPublished - Jul 1 2010



  • Interpregnancy interval
  • Misoprostol
  • Uterine rupture

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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