SFARI Gene 2.0: A community-driven knowledgebase for the autism spectrum disorders (ASDs)

Brett S. Abrahams; Dan E. Arking; Daniel B. Campbell; Heather C. Mefford; Eric M. Morrow; Lauren A. Weiss; Idan Menashe; Tim Wadkins; Sharmila Banerjee-Basu; Alan Packer

doi:10.1186/2040-2392-4-36

SFARI Gene 2.0: A community-driven knowledgebase for the autism spectrum disorders (ASDs)

Brett S. Abrahams, Dan E. Arking, Daniel B. Campbell, Heather C. Mefford, Eric M. Morrow, Lauren A. Weiss, Idan Menashe, Tim Wadkins, Sharmila Banerjee-Basu, Alan Packer

Genetics

Research output: Contribution to journal › Article › peer-review

469 Scopus citations

Abstract

New technologies enabling genome-wide interrogation have led to a large and rapidly growing number of autism spectrum disorder (ASD) candidate genes. Although encouraging, the volume and complexity of these data make it challenging for scientists, particularly non-geneticists, to comprehensively evaluate available evidence for individual genes. Described here is the Gene Scoring module within SFARI Gene 2.0 (), a platform developed to enable systematic community driven assessment of genetic evidence for individual genes with regard to ASD.

Original language	English (US)
Article number	36
Journal	Molecular Autism
Volume	4
Issue number	1
DOIs	https://doi.org/10.1186/2040-2392-4-36
State	Published - 2013

ASJC Scopus subject areas

Molecular Biology
Developmental Neuroscience
Developmental Biology
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1186/2040-2392-4-36

Cite this

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title = "SFARI Gene 2.0: A community-driven knowledgebase for the autism spectrum disorders (ASDs)",

abstract = "New technologies enabling genome-wide interrogation have led to a large and rapidly growing number of autism spectrum disorder (ASD) candidate genes. Although encouraging, the volume and complexity of these data make it challenging for scientists, particularly non-geneticists, to comprehensively evaluate available evidence for individual genes. Described here is the Gene Scoring module within SFARI Gene 2.0 (), a platform developed to enable systematic community driven assessment of genetic evidence for individual genes with regard to ASD.",

author = "Abrahams, {Brett S.} and Arking, {Dan E.} and Campbell, {Daniel B.} and Mefford, {Heather C.} and Morrow, {Eric M.} and Weiss, {Lauren A.} and Idan Menashe and Tim Wadkins and Sharmila Banerjee-Basu and Alan Packer",

note = "Funding Information: SFARI Gene 2.0 is funded by the Simons Foundation. The portal developed for this work was created by Ravi Kollu at MindSpec. We thank members of the Simons Foundation Autism Research Initiative staff for helpful feedback and support, including: G. Fischbach, D. Choi, M. Carlson, J. Spiro, M. Benedetti, A. Mandavilli, A. Tauro-Greenberg and C. Fleisch.",

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doi = "10.1186/2040-2392-4-36",

language = "English (US)",

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journal = "Molecular Autism",

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AU - Arking, Dan E.

AU - Campbell, Daniel B.

AU - Mefford, Heather C.

AU - Morrow, Eric M.

AU - Weiss, Lauren A.

AU - Menashe, Idan

AU - Wadkins, Tim

AU - Banerjee-Basu, Sharmila

AU - Packer, Alan

N1 - Funding Information: SFARI Gene 2.0 is funded by the Simons Foundation. The portal developed for this work was created by Ravi Kollu at MindSpec. We thank members of the Simons Foundation Autism Research Initiative staff for helpful feedback and support, including: G. Fischbach, D. Choi, M. Carlson, J. Spiro, M. Benedetti, A. Mandavilli, A. Tauro-Greenberg and C. Fleisch.

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SFARI Gene 2.0: A community-driven knowledgebase for the autism spectrum disorders (ASDs)

Abstract

ASJC Scopus subject areas

UN SDGs

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