Sequential antiretroviral adherence measurement using electronic bottle cap monitors in a cohort of HIV-infected adults

Jonathan Shuter; Julie A. Sarlo; Roxann O. Stubbs; Richard A. Rode; Barry S. Zingman

doi:10.1177/1545109711420498

Sequential antiretroviral adherence measurement using electronic bottle cap monitors in a cohort of HIV-infected adults

Jonathan Shuter, Julie A. Sarlo, Roxann O. Stubbs, Richard A. Rode, Barry S. Zingman

Medicine

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Most studies employing electronic bottle monitors to measure antiretroviral adherence are limited to 24 weeks of duration, providing a snapshot of adherence from a treatment course that may be lifelong. The stability of these measures in individual patients over time has not been previously described. We measured antiretroviral adherence using Medication Event Monitoring System (MEMS) caps in a patient cohort in 2004 and 2005 and repeated the measurement in 2008 and 2009. Forty-eight participants completed both monitoring periods. Mean adherence rates in the first and second periods were 74.2% and 68.9%, respectively. Adherence rates from the 2 periods for individual participants were highly correlated (Spearman rho =.66, P <.001).

Original language	English (US)
Pages (from-to)	94-97
Number of pages	4
Journal	Journal of the International Association of Physicians in AIDS Care
Volume	11
Issue number	2
DOIs	https://doi.org/10.1177/1545109711420498
State	Published - Mar 2012

Keywords

AIDS
HIV
MEMS
adherence

ASJC Scopus subject areas

Immunology
Dermatology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Sequential antiretroviral adherence measurement using electronic bottle cap monitors in a cohort of HIV-infected adults",

abstract = "Most studies employing electronic bottle monitors to measure antiretroviral adherence are limited to 24 weeks of duration, providing a snapshot of adherence from a treatment course that may be lifelong. The stability of these measures in individual patients over time has not been previously described. We measured antiretroviral adherence using Medication Event Monitoring System (MEMS) caps in a patient cohort in 2004 and 2005 and repeated the measurement in 2008 and 2009. Forty-eight participants completed both monitoring periods. Mean adherence rates in the first and second periods were 74.2% and 68.9%, respectively. Adherence rates from the 2 periods for individual participants were highly correlated (Spearman rho =.66, P <.001).",

keywords = "AIDS, HIV, MEMS, adherence",

author = "Jonathan Shuter and Sarlo, {Julie A.} and Stubbs, {Roxann O.} and Rode, {Richard A.} and Zingman, {Barry S.}",

note = "Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: supported by a grant from the Abbott Laboratories investigator initiated research program and by the Clinical Core of the Center for AIDS Research at the Albert Einstein College of Medicine and Montefiore Medical Center funded by the National Institutes of Health (NIH AI-51519). It was registered with the ClinicalTrials.gov protocol registration system, NCT00785616.",

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AU - Stubbs, Roxann O.

AU - Rode, Richard A.

AU - Zingman, Barry S.

N1 - Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: supported by a grant from the Abbott Laboratories investigator initiated research program and by the Clinical Core of the Center for AIDS Research at the Albert Einstein College of Medicine and Montefiore Medical Center funded by the National Institutes of Health (NIH AI-51519). It was registered with the ClinicalTrials.gov protocol registration system, NCT00785616.

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KW - HIV

KW - MEMS

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Sequential antiretroviral adherence measurement using electronic bottle cap monitors in a cohort of HIV-infected adults

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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