@article{00ec208d39bf4c8599632725be4b68b2,
title = "Septate junction disruption and surface reorganization by non-lethal Ca2+ shock",
abstract = "Using potassium pyroantimonate as a Ca2+ chelating agent, we have been able to open the belt desmosome that mechanically couples adjacent ciliated lateral (L) gill epithelial cells of freshwater mussels. Subsequent transfer of the mechanically uncoupled epithelia to solutions containing millimolar Ca2+ results in dramatic alterations in cell shape and partial disruption and apical reorientation of L cell septate junction. The cells remain viable throughout the procedure as determined by the persistence of ciliary activity, although disruption is accompanied by a separation of neighboring groups of cilia and a switch from metachronal to synchronous L cell ciliary beat co-ordination.",
author = "William Reed and Peter Satir",
note = "Funding Information: The freshwater mussel gill is lined by a simple columnar ciliated epithclium whose junctional structure is typical of invertebrates (see Table 1, Satir and Gilula 1970). For example, each ciliated lateral (L) cell is joined to its neighbors by a belt desmosome and an underlying pleated type septate junction. The ca. 0.5 urn long belt desmosorne (BD) is presumed to function in part in securing each cell to its neighbor. The cytoplasrnic surface of the BD is associated with nicrofilaments that are peripheral elements of the terminal web and that define and probably maintain apical cell shape and organellar pattern. microfilaments have motile capabilities that may be used to alter cell shape. Support for this includes the original descriptive observations on developing systems by Cloney (1966) and others (Baker and Schroeder, 1967; Wessels et. al., 1968), the localization of actin (Ishikawa et. al., 1969; Pollard and Weihing, 1974) *To whom correspondence should be addressed. This work was supported by grants from the USPHS (HL22560 and GM27859)",
year = "1981",
month = may,
doi = "10.1016/0309-1651(81)90174-0",
language = "English (US)",
volume = "5",
pages = "469--478",
journal = "Cell Biology International Reports",
issn = "1065-6995",
publisher = "Portland Press Ltd.",
number = "5",
}