Sensory contributions to impaired prosodic processing in schizophrenia

David I. Leitman, John J. Foxe, Pamela D. Butler, Alice Saperstein, Nadine Revheim, Daniel C. Javitt

Research output: Contribution to journalArticle

147 Citations (Scopus)

Abstract

Background: Deficits in affect recognition are prominent features of schizophrenia. Within the auditory domain, patients show difficulty in interpreting vocal emotional cues based on intonation (prosody). The relationship of these symptoms to deficits in basic sensory processing has not been previously evaluated. Methods: Forty-three patients and 34 healthy comparison subjects were tested on two affective prosody measures: voice emotion identification and voice emotion discrimination. Basic auditory sensory processing was measured using a tone-matching paradigm and the Distorted Tunes Test (DTT). A subset of subjects was also tested on facial affect identification and discrimination tasks. Results: Patients showed significantly impaired performance on all emotion processing tasks. Within the patient group, a principal components analysis demonstrated significant intercorrelations between basic pitch perception and affective prosodic performance. In contrast, facial affect recognition deficits represented a distinct second component. Prosodic affect measures correlated significantly with severity of negative symptoms and impaired global outcome. Conclusions: These results demonstrate significant relationships between basic auditory processing deficits and impaired receptive prosody in schizophrenia. The separate loading of auditory and visual affective recognition measures suggests that within-modality factors may be more significant than cross-modality factors in the etiology of affect recognition deficits in schizophrenia.

Original languageEnglish (US)
Pages (from-to)56-61
Number of pages6
JournalBiological Psychiatry
Volume58
Issue number1
DOIs
StatePublished - Jul 1 2005
Externally publishedYes

Fingerprint

Schizophrenia
Emotions
Pitch Perception
Principal Component Analysis
Cues
Healthy Volunteers
Recognition (Psychology)
Discrimination (Psychology)

Keywords

  • Auditory
  • Emotion
  • Face recognition
  • Prosody
  • Schizophrenia
  • Visual

ASJC Scopus subject areas

  • Biological Psychiatry

Cite this

Leitman, D. I., Foxe, J. J., Butler, P. D., Saperstein, A., Revheim, N., & Javitt, D. C. (2005). Sensory contributions to impaired prosodic processing in schizophrenia. Biological Psychiatry, 58(1), 56-61. https://doi.org/10.1016/j.biopsych.2005.02.034

Sensory contributions to impaired prosodic processing in schizophrenia. / Leitman, David I.; Foxe, John J.; Butler, Pamela D.; Saperstein, Alice; Revheim, Nadine; Javitt, Daniel C.

In: Biological Psychiatry, Vol. 58, No. 1, 01.07.2005, p. 56-61.

Research output: Contribution to journalArticle

Leitman, DI, Foxe, JJ, Butler, PD, Saperstein, A, Revheim, N & Javitt, DC 2005, 'Sensory contributions to impaired prosodic processing in schizophrenia', Biological Psychiatry, vol. 58, no. 1, pp. 56-61. https://doi.org/10.1016/j.biopsych.2005.02.034
Leitman DI, Foxe JJ, Butler PD, Saperstein A, Revheim N, Javitt DC. Sensory contributions to impaired prosodic processing in schizophrenia. Biological Psychiatry. 2005 Jul 1;58(1):56-61. https://doi.org/10.1016/j.biopsych.2005.02.034
Leitman, David I. ; Foxe, John J. ; Butler, Pamela D. ; Saperstein, Alice ; Revheim, Nadine ; Javitt, Daniel C. / Sensory contributions to impaired prosodic processing in schizophrenia. In: Biological Psychiatry. 2005 ; Vol. 58, No. 1. pp. 56-61.
@article{16b1f90ba1844f23995e42a576e6f461,
title = "Sensory contributions to impaired prosodic processing in schizophrenia",
abstract = "Background: Deficits in affect recognition are prominent features of schizophrenia. Within the auditory domain, patients show difficulty in interpreting vocal emotional cues based on intonation (prosody). The relationship of these symptoms to deficits in basic sensory processing has not been previously evaluated. Methods: Forty-three patients and 34 healthy comparison subjects were tested on two affective prosody measures: voice emotion identification and voice emotion discrimination. Basic auditory sensory processing was measured using a tone-matching paradigm and the Distorted Tunes Test (DTT). A subset of subjects was also tested on facial affect identification and discrimination tasks. Results: Patients showed significantly impaired performance on all emotion processing tasks. Within the patient group, a principal components analysis demonstrated significant intercorrelations between basic pitch perception and affective prosodic performance. In contrast, facial affect recognition deficits represented a distinct second component. Prosodic affect measures correlated significantly with severity of negative symptoms and impaired global outcome. Conclusions: These results demonstrate significant relationships between basic auditory processing deficits and impaired receptive prosody in schizophrenia. The separate loading of auditory and visual affective recognition measures suggests that within-modality factors may be more significant than cross-modality factors in the etiology of affect recognition deficits in schizophrenia.",
keywords = "Auditory, Emotion, Face recognition, Prosody, Schizophrenia, Visual",
author = "Leitman, {David I.} and Foxe, {John J.} and Butler, {Pamela D.} and Alice Saperstein and Nadine Revheim and Javitt, {Daniel C.}",
year = "2005",
month = "7",
day = "1",
doi = "10.1016/j.biopsych.2005.02.034",
language = "English (US)",
volume = "58",
pages = "56--61",
journal = "Biological Psychiatry",
issn = "0006-3223",
publisher = "Elsevier USA",
number = "1",

}

TY - JOUR

T1 - Sensory contributions to impaired prosodic processing in schizophrenia

AU - Leitman, David I.

AU - Foxe, John J.

AU - Butler, Pamela D.

AU - Saperstein, Alice

AU - Revheim, Nadine

AU - Javitt, Daniel C.

PY - 2005/7/1

Y1 - 2005/7/1

N2 - Background: Deficits in affect recognition are prominent features of schizophrenia. Within the auditory domain, patients show difficulty in interpreting vocal emotional cues based on intonation (prosody). The relationship of these symptoms to deficits in basic sensory processing has not been previously evaluated. Methods: Forty-three patients and 34 healthy comparison subjects were tested on two affective prosody measures: voice emotion identification and voice emotion discrimination. Basic auditory sensory processing was measured using a tone-matching paradigm and the Distorted Tunes Test (DTT). A subset of subjects was also tested on facial affect identification and discrimination tasks. Results: Patients showed significantly impaired performance on all emotion processing tasks. Within the patient group, a principal components analysis demonstrated significant intercorrelations between basic pitch perception and affective prosodic performance. In contrast, facial affect recognition deficits represented a distinct second component. Prosodic affect measures correlated significantly with severity of negative symptoms and impaired global outcome. Conclusions: These results demonstrate significant relationships between basic auditory processing deficits and impaired receptive prosody in schizophrenia. The separate loading of auditory and visual affective recognition measures suggests that within-modality factors may be more significant than cross-modality factors in the etiology of affect recognition deficits in schizophrenia.

AB - Background: Deficits in affect recognition are prominent features of schizophrenia. Within the auditory domain, patients show difficulty in interpreting vocal emotional cues based on intonation (prosody). The relationship of these symptoms to deficits in basic sensory processing has not been previously evaluated. Methods: Forty-three patients and 34 healthy comparison subjects were tested on two affective prosody measures: voice emotion identification and voice emotion discrimination. Basic auditory sensory processing was measured using a tone-matching paradigm and the Distorted Tunes Test (DTT). A subset of subjects was also tested on facial affect identification and discrimination tasks. Results: Patients showed significantly impaired performance on all emotion processing tasks. Within the patient group, a principal components analysis demonstrated significant intercorrelations between basic pitch perception and affective prosodic performance. In contrast, facial affect recognition deficits represented a distinct second component. Prosodic affect measures correlated significantly with severity of negative symptoms and impaired global outcome. Conclusions: These results demonstrate significant relationships between basic auditory processing deficits and impaired receptive prosody in schizophrenia. The separate loading of auditory and visual affective recognition measures suggests that within-modality factors may be more significant than cross-modality factors in the etiology of affect recognition deficits in schizophrenia.

KW - Auditory

KW - Emotion

KW - Face recognition

KW - Prosody

KW - Schizophrenia

KW - Visual

UR - http://www.scopus.com/inward/record.url?scp=21344445017&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=21344445017&partnerID=8YFLogxK

U2 - 10.1016/j.biopsych.2005.02.034

DO - 10.1016/j.biopsych.2005.02.034

M3 - Article

C2 - 15992523

AN - SCOPUS:21344445017

VL - 58

SP - 56

EP - 61

JO - Biological Psychiatry

JF - Biological Psychiatry

SN - 0006-3223

IS - 1

ER -