Semi-automated analysis of color M-mode echocardiographic images for determining transmitral pressure gradients using a simplified Euler equation

Michael S. Firstenberg, Neil L. Greenberg, Mario J. Garcia, Peter L. Castro, David L. Prior, Nicholas G. Smedira, James D. Thomas

Research output: Contribution to journalConference article

1 Scopus citations


We hypothesize that a simplified version of the Euler equation (SEE) utilizing differences in velocity over a distance and time as obtained by Color Doppler M-mode (CMM) echocardiography can approximate actual peak transmitral pressure gradients (ΔPTM). Methods: In 14 patients undergoing open-heart surgery, ΔPTM was measured under various hemodynamic conditions using 2 high fidelity transducers, 5 cm apart. Transesophageal CMM images were simultaneously acquired and a customized image analysis application was used to abstract spatiotemporal velocity characteristics. Using both the SEE and a simplified Bernoulli equations, ΔPTM were determined and compared to the actual ΔPTM. Results: While the simplified Bernoulli equation resulted in a poor estimate (y = 0.075x+0.71, r = 0.45), the ΔPTM obtained using the SEE correlated strongly (y = 0.79x+0.48, r = 0.91) with the actual measurements. Conclusions: Semi-automated analysis of CMM images using a SEE can accurately estimate actual ΔPTM.

Original languageEnglish (US)
Pages (from-to)181-184
Number of pages4
JournalComputers in Cardiology
StatePublished - Dec 1 1999
Externally publishedYes
EventThe 26th Annual Meeting: Computers in Cardiology 1999 - Hannover, Ger
Duration: Sep 26 1999Sep 29 1999


ASJC Scopus subject areas

  • Computer Science Applications
  • Cardiology and Cardiovascular Medicine

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