Self-reported bacterial infections among women with or at risk for human immunodeficiency virus infection

Timothy P. Flanigan, J. W. Hogan, D. Smith, E. Schoenbaum, D. Vlahov, P. Schuman, K. Mayer

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Bacterial infections are a major cause of morbidity and mortality in persons with human immunodeficiency virus (HIV) infection, particularly women. We performed a cross-sectional analysis of a history of bacterial infections among 1,310 women with or at risk for HIV infection. HIV- seropositive women were significantly more likely than seronegative women to report recent and lifetime histories of bacterial infection, even after history of injection drug use since 1977 was adjusted for; this included recent pneumonia (odds ratio [OR], 3.2; 95% confidence interval [CI], 1.5- 6.6), sinusitis (OR, 1.4; 95% CI, 1.0-2.0), and urinary tract infection (OR, 1.5; 95% CI, 1.1-2.1). Compared with HIV-negative women, women with CD4 cell counts of <200 were about eight times more likely to report recent pneumonia (OR, 7.8; 95% CI, 3.4-17.7); those with CD4 cell counts of 200-500 were almost three times more likely to do so (OR, 2.6; CI, 1.2-5.7). Logistic regression analysis revealed that only CD4 cell category and a recent history of smoking had a significant relationship to self-reported pneumonia.

Original languageEnglish (US)
Pages (from-to)608-612
Number of pages5
JournalClinical Infectious Diseases
Volume29
Issue number3
DOIs
StatePublished - Jan 1 1999

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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