TY - JOUR
T1 - Self-administered nitrous oxide
T2 - An adjunct analgesic
AU - Flomenbaum, Neal
AU - John Gallagher, E.
AU - Eagen, Kathleen
AU - Jacobson, Sheldon
PY - 1979/3
Y1 - 1979/3
N2 - In a pilot study of 26 patients, a mixture of 50% nitrous oxide and 50% oxygen (N2O-O2) appeared to be an effective and safe analgesic for the incision and drainage of closed-space infections. The analgesic effect of N2O-O2, as measured by a Mean Analgesic Index, is augmented by both amnesic and dissociative effects, ie, patients remembered experiencing significantly less pain than they complained of during the procedure (p < .01) and reported significantly more pain than they appeared to be having, as recorded by an observer (p < .01). The patient's recollected pain, however, correlated well (r = .68) with the observer's assessment. Forty-two percent of patients had undergone a similar or identical procedure in the past without the benefit of N2O-O2 and made uniformly favorable comparative statements concerning the analgesic effect of the gas.
AB - In a pilot study of 26 patients, a mixture of 50% nitrous oxide and 50% oxygen (N2O-O2) appeared to be an effective and safe analgesic for the incision and drainage of closed-space infections. The analgesic effect of N2O-O2, as measured by a Mean Analgesic Index, is augmented by both amnesic and dissociative effects, ie, patients remembered experiencing significantly less pain than they complained of during the procedure (p < .01) and reported significantly more pain than they appeared to be having, as recorded by an observer (p < .01). The patient's recollected pain, however, correlated well (r = .68) with the observer's assessment. Forty-two percent of patients had undergone a similar or identical procedure in the past without the benefit of N2O-O2 and made uniformly favorable comparative statements concerning the analgesic effect of the gas.
KW - nitrous oxide, analgesic
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U2 - 10.1016/S0361-1124(79)80149-5
DO - 10.1016/S0361-1124(79)80149-5
M3 - Article
C2 - 513425
AN - SCOPUS:0018344763
SN - 0361-1124
VL - 8
SP - 95
EP - 97
JO - Journal of the American College of Emergency Physicians
JF - Journal of the American College of Emergency Physicians
IS - 3
ER -