Self-administered nitrous oxide: An adjunct analgesic

Neal Flomenbaum, E. John Gallagher, Kathleen Eagen, Sheldon Jacobson

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

In a pilot study of 26 patients, a mixture of 50% nitrous oxide and 50% oxygen (N2O-O2) appeared to be an effective and safe analgesic for the incision and drainage of closed-space infections. The analgesic effect of N2O-O2, as measured by a Mean Analgesic Index, is augmented by both amnesic and dissociative effects, ie, patients remembered experiencing significantly less pain than they complained of during the procedure (p < .01) and reported significantly more pain than they appeared to be having, as recorded by an observer (p < .01). The patient's recollected pain, however, correlated well (r = .68) with the observer's assessment. Forty-two percent of patients had undergone a similar or identical procedure in the past without the benefit of N2O-O2 and made uniformly favorable comparative statements concerning the analgesic effect of the gas.

Original languageEnglish (US)
Pages (from-to)95-97
Number of pages3
JournalJournal of the American College of Emergency Physicians
Volume8
Issue number3
DOIs
StatePublished - 1979

Fingerprint

Nitrous Oxide
Analgesics
Pain
Drainage
Gases
Oxygen
Infection

Keywords

  • nitrous oxide, analgesic

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

Self-administered nitrous oxide : An adjunct analgesic. / Flomenbaum, Neal; Gallagher, E. John; Eagen, Kathleen; Jacobson, Sheldon.

In: Journal of the American College of Emergency Physicians, Vol. 8, No. 3, 1979, p. 95-97.

Research output: Contribution to journalArticle

Flomenbaum, Neal ; Gallagher, E. John ; Eagen, Kathleen ; Jacobson, Sheldon. / Self-administered nitrous oxide : An adjunct analgesic. In: Journal of the American College of Emergency Physicians. 1979 ; Vol. 8, No. 3. pp. 95-97.
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