Selenium in Parenteral Nutrition

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The essential nature of selenium in human health was established in the 1970s, with the description of clinical manifestations of deficiency in humans receiving Se-free parenteral nutrition (TPN) coinciding with the report of the association between Keshan disease and Se deficiency. Multiple reports of Se deficiency in patients receiving Se-free TPN have led to current recommendations to include Se routinely in TPN formulations. Parenteral Se is available as sodium selenite or selenious acid, either as part of a trace-element package or as a separate intravenous preparation. Guidelines for parenteral Se dosing have evolved over the past 40 years, with the goal to prevent deficiency and optimize health in the adult, pediatric and neonatal populations, with attention given to the altered metabolic requirements in disease states.

Original languageEnglish (US)
Title of host publicationBetaine: Chemistry, Analysis, Function and Effects
PublisherRoyal Society of Chemistry
Pages291-303
Number of pages13
Volume2015-January
Edition9
DOIs
StatePublished - 2015

Publication series

NameFood and Nutritional Components in Focus
Number9
Volume2015-January
ISSN (Print)20451695
ISSN (Electronic)20451709

Fingerprint

sodium selenite
Parenteral Nutrition
parenteral feeding
Nutrition
Selenium
selenium
human health
trace elements
Health
Sodium Selenite
Selenious Acid
Pediatrics
acids
Trace Elements
Guidelines
Population
Keshan disease

ASJC Scopus subject areas

  • Food Science
  • Analytical Chemistry

Cite this

Miller, M., & Burjonrappa, S. (2015). Selenium in Parenteral Nutrition. In Betaine: Chemistry, Analysis, Function and Effects (9 ed., Vol. 2015-January, pp. 291-303). (Food and Nutritional Components in Focus; Vol. 2015-January, No. 9). Royal Society of Chemistry. https://doi.org/10.1039/9781782622215-00291

Selenium in Parenteral Nutrition. / Miller, Malki; Burjonrappa, Sathyaprasad.

Betaine: Chemistry, Analysis, Function and Effects. Vol. 2015-January 9. ed. Royal Society of Chemistry, 2015. p. 291-303 (Food and Nutritional Components in Focus; Vol. 2015-January, No. 9).

Research output: Chapter in Book/Report/Conference proceedingChapter

Miller, M & Burjonrappa, S 2015, Selenium in Parenteral Nutrition. in Betaine: Chemistry, Analysis, Function and Effects. 9 edn, vol. 2015-January, Food and Nutritional Components in Focus, no. 9, vol. 2015-January, Royal Society of Chemistry, pp. 291-303. https://doi.org/10.1039/9781782622215-00291
Miller M, Burjonrappa S. Selenium in Parenteral Nutrition. In Betaine: Chemistry, Analysis, Function and Effects. 9 ed. Vol. 2015-January. Royal Society of Chemistry. 2015. p. 291-303. (Food and Nutritional Components in Focus; 9). https://doi.org/10.1039/9781782622215-00291
Miller, Malki ; Burjonrappa, Sathyaprasad. / Selenium in Parenteral Nutrition. Betaine: Chemistry, Analysis, Function and Effects. Vol. 2015-January 9. ed. Royal Society of Chemistry, 2015. pp. 291-303 (Food and Nutritional Components in Focus; 9).
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