Screening for Cancer in Persons Living with HIV Infection

James J. Goedert, Howard D. Hosgood, Robert J. Biggar, Howard Strickler, Charles S. Rabkin

Research output: Contribution to journalReview article

9 Citations (Scopus)

Abstract

Survival with human immunodeficiency virus (HIV) infection has greatly improved due to effective antiretroviral therapy (ART). As infectious complications have declined, malignancy now accounts for over one-third of deaths among people living with HIV (PLWH). Based on practices in the general population, cancer screening of PLWH can decrease both morbidity and mortality. In this article, we review and consider directed approaches for colorectal, breast, cervical, and lung cancer screening. Furthermore, routine physical examinations may detect lymphomas and skin, anal, and oral cancers. Comprehensive cancer prevention in PLWH should also include ART adherence, vaccination against oncogenic viruses, treatment of hepatitis viruses, and smoking cessation. Cancer screening for PLWH warrants further research on safety and efficacy as well as targeted efforts to increase adherence.

Original languageEnglish (US)
Pages (from-to)416-428
Number of pages13
JournalTrends in Cancer
Volume2
Issue number8
DOIs
StatePublished - Aug 1 2016

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Virus Diseases
Early Detection of Cancer
HIV
Anus Neoplasms
Oncogenic Viruses
Hepatitis Viruses
Mouth Neoplasms
Skin Neoplasms
Smoking Cessation
Uterine Cervical Neoplasms
General Practice
Physical Examination
Colorectal Neoplasms
Lymphoma
Lung Neoplasms
Neoplasms
Vaccination
Therapeutics
Breast Neoplasms
Morbidity

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Screening for Cancer in Persons Living with HIV Infection. / Goedert, James J.; Hosgood, Howard D.; Biggar, Robert J.; Strickler, Howard; Rabkin, Charles S.

In: Trends in Cancer, Vol. 2, No. 8, 01.08.2016, p. 416-428.

Research output: Contribution to journalReview article

Goedert, James J. ; Hosgood, Howard D. ; Biggar, Robert J. ; Strickler, Howard ; Rabkin, Charles S. / Screening for Cancer in Persons Living with HIV Infection. In: Trends in Cancer. 2016 ; Vol. 2, No. 8. pp. 416-428.
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