TY - JOUR
T1 - Screening for Cancer in Persons Living with HIV Infection
AU - Goedert, James J.
AU - Hosgood, H. Dean
AU - Biggar, Robert J.
AU - Strickler, Howard D.
AU - Rabkin, Charles S.
N1 - Publisher Copyright:
© 2016
PY - 2016/8/1
Y1 - 2016/8/1
N2 - Survival with human immunodeficiency virus (HIV) infection has greatly improved due to effective antiretroviral therapy (ART). As infectious complications have declined, malignancy now accounts for over one-third of deaths among people living with HIV (PLWH). Based on practices in the general population, cancer screening of PLWH can decrease both morbidity and mortality. In this article, we review and consider directed approaches for colorectal, breast, cervical, and lung cancer screening. Furthermore, routine physical examinations may detect lymphomas and skin, anal, and oral cancers. Comprehensive cancer prevention in PLWH should also include ART adherence, vaccination against oncogenic viruses, treatment of hepatitis viruses, and smoking cessation. Cancer screening for PLWH warrants further research on safety and efficacy as well as targeted efforts to increase adherence.
AB - Survival with human immunodeficiency virus (HIV) infection has greatly improved due to effective antiretroviral therapy (ART). As infectious complications have declined, malignancy now accounts for over one-third of deaths among people living with HIV (PLWH). Based on practices in the general population, cancer screening of PLWH can decrease both morbidity and mortality. In this article, we review and consider directed approaches for colorectal, breast, cervical, and lung cancer screening. Furthermore, routine physical examinations may detect lymphomas and skin, anal, and oral cancers. Comprehensive cancer prevention in PLWH should also include ART adherence, vaccination against oncogenic viruses, treatment of hepatitis viruses, and smoking cessation. Cancer screening for PLWH warrants further research on safety and efficacy as well as targeted efforts to increase adherence.
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U2 - 10.1016/j.trecan.2016.06.007
DO - 10.1016/j.trecan.2016.06.007
M3 - Review article
C2 - 27891533
AN - SCOPUS:84995487689
SN - 2405-8033
VL - 2
SP - 416
EP - 428
JO - Trends in Cancer
JF - Trends in Cancer
IS - 8
ER -