Sarcoidosis diagnosed after september 11, 2001, among adults exposed to the world trade center disaster

Hannah T. Jordan, Steven D. Stellman, David J. Prezant, Alvin Teirstein, Sukhminder S. Osahan, James E. Cone

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Objective: Explore relationships between World Trade Center (WTC) exposures and sarcoidosis. Methods: Sarcoidosis has been reported after exposure to the WTC disaster. We ascertained biopsy-proven post-9/11 sarcoidosis among WTC Health Registry enrollees. Cases diagnosed after Registry enrollment were included in a nested case-control study. Controls were matched to cases on age, sex, race or ethnicity, and eligibility group (eg, rescue or recovery worker). Results: We identified 43 cases of post-9/11 sarcoidosis. Twenty-eight incident cases and 109 controls were included in the case-control analysis. Working on the WTC debris pile was associated with sarcoidosis (odds ratio 9.1, 95% confidence interval 1.1 to 74.0), but WTC dust cloud exposure was not (odds ratio 1.0, 95% confidence interval 0.4 to 2.8). Conclusions: Working on the WTC debris pile was associated with an elevated risk of post-9/11 sarcoidosis. Occupationally exposed workers may be at increased risk.

Original languageEnglish (US)
Pages (from-to)966-974
Number of pages9
JournalJournal of Occupational and Environmental Medicine
Volume53
Issue number9
DOIs
StatePublished - Sep 2011

Fingerprint

Disasters
Sarcoidosis
Registries
Odds Ratio
Confidence Intervals
Dust
Case-Control Studies
Biopsy
Health

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Sarcoidosis diagnosed after september 11, 2001, among adults exposed to the world trade center disaster. / Jordan, Hannah T.; Stellman, Steven D.; Prezant, David J.; Teirstein, Alvin; Osahan, Sukhminder S.; Cone, James E.

In: Journal of Occupational and Environmental Medicine, Vol. 53, No. 9, 09.2011, p. 966-974.

Research output: Contribution to journalArticle

Jordan, Hannah T. ; Stellman, Steven D. ; Prezant, David J. ; Teirstein, Alvin ; Osahan, Sukhminder S. ; Cone, James E. / Sarcoidosis diagnosed after september 11, 2001, among adults exposed to the world trade center disaster. In: Journal of Occupational and Environmental Medicine. 2011 ; Vol. 53, No. 9. pp. 966-974.
@article{9bf67c2d944e4f35a25ee39f20166e0c,
title = "Sarcoidosis diagnosed after september 11, 2001, among adults exposed to the world trade center disaster",
abstract = "Objective: Explore relationships between World Trade Center (WTC) exposures and sarcoidosis. Methods: Sarcoidosis has been reported after exposure to the WTC disaster. We ascertained biopsy-proven post-9/11 sarcoidosis among WTC Health Registry enrollees. Cases diagnosed after Registry enrollment were included in a nested case-control study. Controls were matched to cases on age, sex, race or ethnicity, and eligibility group (eg, rescue or recovery worker). Results: We identified 43 cases of post-9/11 sarcoidosis. Twenty-eight incident cases and 109 controls were included in the case-control analysis. Working on the WTC debris pile was associated with sarcoidosis (odds ratio 9.1, 95{\%} confidence interval 1.1 to 74.0), but WTC dust cloud exposure was not (odds ratio 1.0, 95{\%} confidence interval 0.4 to 2.8). Conclusions: Working on the WTC debris pile was associated with an elevated risk of post-9/11 sarcoidosis. Occupationally exposed workers may be at increased risk.",
author = "Jordan, {Hannah T.} and Stellman, {Steven D.} and Prezant, {David J.} and Alvin Teirstein and Osahan, {Sukhminder S.} and Cone, {James E.}",
year = "2011",
month = "9",
doi = "10.1097/JOM.0b013e31822a3596",
language = "English (US)",
volume = "53",
pages = "966--974",
journal = "Journal of Occupational and Environmental Medicine",
issn = "1076-2752",
publisher = "Lippincott Williams and Wilkins",
number = "9",

}

TY - JOUR

T1 - Sarcoidosis diagnosed after september 11, 2001, among adults exposed to the world trade center disaster

AU - Jordan, Hannah T.

AU - Stellman, Steven D.

AU - Prezant, David J.

AU - Teirstein, Alvin

AU - Osahan, Sukhminder S.

AU - Cone, James E.

PY - 2011/9

Y1 - 2011/9

N2 - Objective: Explore relationships between World Trade Center (WTC) exposures and sarcoidosis. Methods: Sarcoidosis has been reported after exposure to the WTC disaster. We ascertained biopsy-proven post-9/11 sarcoidosis among WTC Health Registry enrollees. Cases diagnosed after Registry enrollment were included in a nested case-control study. Controls were matched to cases on age, sex, race or ethnicity, and eligibility group (eg, rescue or recovery worker). Results: We identified 43 cases of post-9/11 sarcoidosis. Twenty-eight incident cases and 109 controls were included in the case-control analysis. Working on the WTC debris pile was associated with sarcoidosis (odds ratio 9.1, 95% confidence interval 1.1 to 74.0), but WTC dust cloud exposure was not (odds ratio 1.0, 95% confidence interval 0.4 to 2.8). Conclusions: Working on the WTC debris pile was associated with an elevated risk of post-9/11 sarcoidosis. Occupationally exposed workers may be at increased risk.

AB - Objective: Explore relationships between World Trade Center (WTC) exposures and sarcoidosis. Methods: Sarcoidosis has been reported after exposure to the WTC disaster. We ascertained biopsy-proven post-9/11 sarcoidosis among WTC Health Registry enrollees. Cases diagnosed after Registry enrollment were included in a nested case-control study. Controls were matched to cases on age, sex, race or ethnicity, and eligibility group (eg, rescue or recovery worker). Results: We identified 43 cases of post-9/11 sarcoidosis. Twenty-eight incident cases and 109 controls were included in the case-control analysis. Working on the WTC debris pile was associated with sarcoidosis (odds ratio 9.1, 95% confidence interval 1.1 to 74.0), but WTC dust cloud exposure was not (odds ratio 1.0, 95% confidence interval 0.4 to 2.8). Conclusions: Working on the WTC debris pile was associated with an elevated risk of post-9/11 sarcoidosis. Occupationally exposed workers may be at increased risk.

UR - http://www.scopus.com/inward/record.url?scp=84860388804&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84860388804&partnerID=8YFLogxK

U2 - 10.1097/JOM.0b013e31822a3596

DO - 10.1097/JOM.0b013e31822a3596

M3 - Article

VL - 53

SP - 966

EP - 974

JO - Journal of Occupational and Environmental Medicine

JF - Journal of Occupational and Environmental Medicine

SN - 1076-2752

IS - 9

ER -