Sarcoidosis diagnosed after september 11, 2001, among adults exposed to the world trade center disaster

Hannah T. Jordan, Steven D. Stellman, David Prezant, Alvin Teirstein, Sukhminder S. Osahan, James E. Cone

Research output: Contribution to journalArticlepeer-review

61 Scopus citations

Abstract

Objective: Explore relationships between World Trade Center (WTC) exposures and sarcoidosis. Methods: Sarcoidosis has been reported after exposure to the WTC disaster. We ascertained biopsy-proven post-9/11 sarcoidosis among WTC Health Registry enrollees. Cases diagnosed after Registry enrollment were included in a nested case-control study. Controls were matched to cases on age, sex, race or ethnicity, and eligibility group (eg, rescue or recovery worker). Results: We identified 43 cases of post-9/11 sarcoidosis. Twenty-eight incident cases and 109 controls were included in the case-control analysis. Working on the WTC debris pile was associated with sarcoidosis (odds ratio 9.1, 95% confidence interval 1.1 to 74.0), but WTC dust cloud exposure was not (odds ratio 1.0, 95% confidence interval 0.4 to 2.8). Conclusions: Working on the WTC debris pile was associated with an elevated risk of post-9/11 sarcoidosis. Occupationally exposed workers may be at increased risk.

Original languageEnglish (US)
Pages (from-to)966-974
Number of pages9
JournalJournal of Occupational and Environmental Medicine
Volume53
Issue number9
DOIs
StatePublished - Sep 2011

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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