TY - JOUR
T1 - Sarcoidosis diagnosed after september 11, 2001, among adults exposed to the world trade center disaster
AU - Jordan, Hannah T.
AU - Stellman, Steven D.
AU - Prezant, David
AU - Teirstein, Alvin
AU - Osahan, Sukhminder S.
AU - Cone, James E.
N1 - Funding Information:
This study was supported by Cooperative Agreement U50/ATU272750 from the Agency for Toxic Substances and Disease Registry of the Centers for Disease Control and Prevention, which included support from the National Center for Environmental Health; the National Institute for Occupational Safety and Health; and the New York City Department of Health and Mental Hygiene.
PY - 2011/9
Y1 - 2011/9
N2 - Objective: Explore relationships between World Trade Center (WTC) exposures and sarcoidosis. Methods: Sarcoidosis has been reported after exposure to the WTC disaster. We ascertained biopsy-proven post-9/11 sarcoidosis among WTC Health Registry enrollees. Cases diagnosed after Registry enrollment were included in a nested case-control study. Controls were matched to cases on age, sex, race or ethnicity, and eligibility group (eg, rescue or recovery worker). Results: We identified 43 cases of post-9/11 sarcoidosis. Twenty-eight incident cases and 109 controls were included in the case-control analysis. Working on the WTC debris pile was associated with sarcoidosis (odds ratio 9.1, 95% confidence interval 1.1 to 74.0), but WTC dust cloud exposure was not (odds ratio 1.0, 95% confidence interval 0.4 to 2.8). Conclusions: Working on the WTC debris pile was associated with an elevated risk of post-9/11 sarcoidosis. Occupationally exposed workers may be at increased risk.
AB - Objective: Explore relationships between World Trade Center (WTC) exposures and sarcoidosis. Methods: Sarcoidosis has been reported after exposure to the WTC disaster. We ascertained biopsy-proven post-9/11 sarcoidosis among WTC Health Registry enrollees. Cases diagnosed after Registry enrollment were included in a nested case-control study. Controls were matched to cases on age, sex, race or ethnicity, and eligibility group (eg, rescue or recovery worker). Results: We identified 43 cases of post-9/11 sarcoidosis. Twenty-eight incident cases and 109 controls were included in the case-control analysis. Working on the WTC debris pile was associated with sarcoidosis (odds ratio 9.1, 95% confidence interval 1.1 to 74.0), but WTC dust cloud exposure was not (odds ratio 1.0, 95% confidence interval 0.4 to 2.8). Conclusions: Working on the WTC debris pile was associated with an elevated risk of post-9/11 sarcoidosis. Occupationally exposed workers may be at increased risk.
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U2 - 10.1097/JOM.0b013e31822a3596
DO - 10.1097/JOM.0b013e31822a3596
M3 - Article
C2 - 21860326
AN - SCOPUS:84860388804
SN - 1076-2752
VL - 53
SP - 966
EP - 974
JO - Journal of Occupational and Environmental Medicine
JF - Journal of Occupational and Environmental Medicine
IS - 9
ER -
