TY - JOUR
T1 - Sarcoidosis-Associated Immune Thrombocytopenic Purpura and Focal Segmental Glomerulosclerosis
AU - Korogodina, Anna
AU - Kaur, Navneet
AU - Kumthekar, Anand
N1 - Publisher Copyright:
© 2022 American Federation for Medical Research.
PY - 2022
Y1 - 2022
N2 - Sarcoidosis is well known for heterogeneity of its presentation and multisystem organ involvement. It commonly involves respiratory tract, skin, eyes, and lymph nodes, as well as hematologic and renal systems. While anemia and lymphopenia are the most common hematologic abnormalities seen in sarcoidosis, immune thrombocytopenic purpura (ITP) is considered rare. Renal abnormalities, although infrequent, are usually more likely to involve tubules rather than glomeruli. In this report, we present a case of sarcoidosis-associated ITP and focal segmental glomerulosclerosis (FSGS), refractory to first-line therapy, but successfully treated with Rituximab and thrombopoietin-receptor agonist.
AB - Sarcoidosis is well known for heterogeneity of its presentation and multisystem organ involvement. It commonly involves respiratory tract, skin, eyes, and lymph nodes, as well as hematologic and renal systems. While anemia and lymphopenia are the most common hematologic abnormalities seen in sarcoidosis, immune thrombocytopenic purpura (ITP) is considered rare. Renal abnormalities, although infrequent, are usually more likely to involve tubules rather than glomeruli. In this report, we present a case of sarcoidosis-associated ITP and focal segmental glomerulosclerosis (FSGS), refractory to first-line therapy, but successfully treated with Rituximab and thrombopoietin-receptor agonist.
KW - Immune thrombocytopenic purpura (ITP)
KW - focal segmental glomerulosclerosis (FSGS)
KW - sarcoidosis
UR - http://www.scopus.com/inward/record.url?scp=85130031082&partnerID=8YFLogxK
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U2 - 10.1177/23247096221097522
DO - 10.1177/23247096221097522
M3 - Article
C2 - 35567301
AN - SCOPUS:85130031082
SN - 2324-7096
VL - 10
JO - Journal of Investigative Medicine High Impact Case Reports
JF - Journal of Investigative Medicine High Impact Case Reports
ER -