TY - JOUR
T1 - Sample Design and Cohort Selection in the Hispanic Community Health Study/Study of Latinos
AU - LaVange, Lisa M.
AU - Kalsbeek, William D.
AU - Sorlie, Paul D.
AU - Avilés-Santa, Larissa M.
AU - Kaplan, Robert C.
AU - Barnhart, Janice
AU - Liu, Kiang
AU - Giachello, Aida
AU - Lee, David J.
AU - Ryan, John
AU - Criqui, Michael H.
AU - Elder, John P.
N1 - Funding Information:
The Hispanic Community Health Study (HCHS)/ Study of Latinos (SOL) is a multicenter community-based cohort study of Hispanics/Latinos in the United States (US). The study objectives are to provide information on the health status and disease burden of US Hispanics/Latinos and to investigate relationships between baseline risk factors and disease incidence during follow-up. A cohort of 16,000 Hispanics/Latinos 18–74 years of age will be enrolled and, on completion of a comprehensive baseline examination, followed annually to determine the incidence of clinical events, including cardiovascular events and pulmonary exacerbations. The study is funded by the National Heart, Lung, and Blood Institute and six other institutes, centers, or offices within the National Institutes of Health. Details of the study design and its various components are described by Sorlie et al. (1) . This paper describes the sample design used to identify and select households and persons for study participation.
Funding Information:
The Hispanic Community Health Study/Study of Latinos is funded by contracts from the National Heart, Lung, and Blood Institute (NHLBI) to the University of North Carolina ( N01-HC65233 ), University of Miami ( N01-HC65234 ), Albert Einstein College of Medicine ( N01-HC65235 ), Northwestern University ( N01-HC65236 ), and San Diego State University ( N01-HC65237 ). The following Institutes/Centers/Offices contribute to the HCHS/SOL through a transfer of funds to the NHLBI: National Center on Minority Health and Health Disparities, the National Institute of Deafness and Other Communications Disorders, the National Institute of Dental and Craniofacial Research, the National Institute of Diabetes and Digestive and Kidney Diseases, the National Institute of Neurological Disorders and Stroke, and the Office of Dietary Supplements.
PY - 2010/8
Y1 - 2010/8
N2 - Purpose: The Hispanic Community Health Study (HCHS)/Study of Latinos (SOL) is a multicenter, community-based cohort study of Hispanic/Latino adults in the United States. A diverse participant sample is required that is both representative of the target population and likely to remain engaged throughout follow-up. The choice of sample design, its rationale, and benefits and challenges of design decisions are described in this study. Methods: The study design calls for recruitment and follow-up of a cohort of 16,000 Hispanics/Latinos 18-74 years of age, with 62.5% (10,000) over 44 years of age and adequate subgroup sample sizes to support inference by Hispanic/Latino background. Participants are recruited in community areas surrounding four field centers in the Bronx, Chicago, Miami, and San Diego. A two-stage area probability sample of households is selected with stratification and oversampling incorporated at each stage to provide a broadly diverse sample, offer efficiencies in field operations, and ensure that the target age distribution is obtained. Conclusions: Embedding probability sampling within this traditional, multisite cohort study design enables competing research objectives to be met. However, the use of probability sampling requires developing solutions to some unique challenges in both sample selection and recruitment, as described here.
AB - Purpose: The Hispanic Community Health Study (HCHS)/Study of Latinos (SOL) is a multicenter, community-based cohort study of Hispanic/Latino adults in the United States. A diverse participant sample is required that is both representative of the target population and likely to remain engaged throughout follow-up. The choice of sample design, its rationale, and benefits and challenges of design decisions are described in this study. Methods: The study design calls for recruitment and follow-up of a cohort of 16,000 Hispanics/Latinos 18-74 years of age, with 62.5% (10,000) over 44 years of age and adequate subgroup sample sizes to support inference by Hispanic/Latino background. Participants are recruited in community areas surrounding four field centers in the Bronx, Chicago, Miami, and San Diego. A two-stage area probability sample of households is selected with stratification and oversampling incorporated at each stage to provide a broadly diverse sample, offer efficiencies in field operations, and ensure that the target age distribution is obtained. Conclusions: Embedding probability sampling within this traditional, multisite cohort study design enables competing research objectives to be met. However, the use of probability sampling requires developing solutions to some unique challenges in both sample selection and recruitment, as described here.
KW - Hispanic/Latino Health
KW - Probability Sampling
KW - Sampling Diverse Populations
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U2 - 10.1016/j.annepidem.2010.05.006
DO - 10.1016/j.annepidem.2010.05.006
M3 - Article
C2 - 20609344
AN - SCOPUS:77954250819
SN - 1047-2797
VL - 20
SP - 642
EP - 649
JO - Annals of Epidemiology
JF - Annals of Epidemiology
IS - 8
ER -