Salivary mucoepidermoid carcinoma revisited

Andrés Coca-Pelaz, Juan P. Rodrigo, Asterios Triantafyllou, Jennifer L. Hunt, Alessandra Rinaldo, Primož Strojan, Missak Haigentz, William M. Mendenhall, Robert P. Takes, Vincent Vander Poorten, Alfio Ferlito

Research output: Contribution to journalReview article

42 Scopus citations

Abstract

Clinicopathological features, prognosis and therapeutic strategies for mucoepidermoid carcinoma originating in salivary and salivary-type glands of the head and neck are reviewed. We emphasise histopathological aspects, appraise the value of histochemistry, electron microscopy, immunohistochemistry and cytophotometry, and discuss histogenesis and characteristic gene translocations. We additionally consider possible diagnostic difficulties, problems related to histological grading and accuracy of existing literature, and areas of controversy or uncertainty which may benefit from further investigations.

Original languageEnglish (US)
Pages (from-to)799-819
Number of pages21
JournalEuropean Archives of Oto-Rhino-Laryngology
Volume272
Issue number4
DOIs
StatePublished - Jan 1 2015

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Keywords

  • Head and neck
  • Mucoepidermoid carcinoma
  • Pathology
  • Prognosis
  • Salivary glands
  • Therapy

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Coca-Pelaz, A., Rodrigo, J. P., Triantafyllou, A., Hunt, J. L., Rinaldo, A., Strojan, P., Haigentz, M., Mendenhall, W. M., Takes, R. P., Vander Poorten, V., & Ferlito, A. (2015). Salivary mucoepidermoid carcinoma revisited. European Archives of Oto-Rhino-Laryngology, 272(4), 799-819. https://doi.org/10.1007/s00405-014-3053-z