Salivary mucoepidermoid carcinoma revisited

Andrés Coca-Pelaz; Juan P. Rodrigo; Asterios Triantafyllou; Jennifer L. Hunt; Alessandra Rinaldo; Primož Strojan; Missak Haigentz; William M. Mendenhall; Robert P. Takes; Vincent Vander Poorten; Alfio Ferlito

doi:10.1007/s00405-014-3053-z

Salivary mucoepidermoid carcinoma revisited

Andrés Coca-Pelaz, Juan P. Rodrigo, Asterios Triantafyllou, Jennifer L. Hunt, Alessandra Rinaldo, Primož Strojan, Missak Haigentz, William M. Mendenhall, Robert P. Takes, Vincent Vander Poorten, Alfio Ferlito

Medicine

Research output: Contribution to journal › Review article › peer-review

77 Scopus citations

Abstract

Clinicopathological features, prognosis and therapeutic strategies for mucoepidermoid carcinoma originating in salivary and salivary-type glands of the head and neck are reviewed. We emphasise histopathological aspects, appraise the value of histochemistry, electron microscopy, immunohistochemistry and cytophotometry, and discuss histogenesis and characteristic gene translocations. We additionally consider possible diagnostic difficulties, problems related to histological grading and accuracy of existing literature, and areas of controversy or uncertainty which may benefit from further investigations.

Original language	English (US)
Pages (from-to)	799-819
Number of pages	21
Journal	European Archives of Oto-Rhino-Laryngology
Volume	272
Issue number	4
DOIs	https://doi.org/10.1007/s00405-014-3053-z
State	Published - Apr 2015

Keywords

Head and neck
Mucoepidermoid carcinoma
Pathology
Prognosis
Salivary glands
Therapy

ASJC Scopus subject areas

Otorhinolaryngology

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10.1007/s00405-014-3053-z

Cite this

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title = "Salivary mucoepidermoid carcinoma revisited",

abstract = "Clinicopathological features, prognosis and therapeutic strategies for mucoepidermoid carcinoma originating in salivary and salivary-type glands of the head and neck are reviewed. We emphasise histopathological aspects, appraise the value of histochemistry, electron microscopy, immunohistochemistry and cytophotometry, and discuss histogenesis and characteristic gene translocations. We additionally consider possible diagnostic difficulties, problems related to histological grading and accuracy of existing literature, and areas of controversy or uncertainty which may benefit from further investigations.",

keywords = "Head and neck, Mucoepidermoid carcinoma, Pathology, Prognosis, Salivary glands, Therapy",

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doi = "10.1007/s00405-014-3053-z",

language = "English (US)",

volume = "272",

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TY - JOUR

T1 - Salivary mucoepidermoid carcinoma revisited

AU - Coca-Pelaz, Andrés

AU - Rodrigo, Juan P.

AU - Triantafyllou, Asterios

AU - Hunt, Jennifer L.

AU - Rinaldo, Alessandra

AU - Strojan, Primož

AU - Haigentz, Missak

AU - Mendenhall, William M.

AU - Takes, Robert P.

AU - Vander Poorten, Vincent

AU - Ferlito, Alfio

PY - 2015/4

Y1 - 2015/4

N2 - Clinicopathological features, prognosis and therapeutic strategies for mucoepidermoid carcinoma originating in salivary and salivary-type glands of the head and neck are reviewed. We emphasise histopathological aspects, appraise the value of histochemistry, electron microscopy, immunohistochemistry and cytophotometry, and discuss histogenesis and characteristic gene translocations. We additionally consider possible diagnostic difficulties, problems related to histological grading and accuracy of existing literature, and areas of controversy or uncertainty which may benefit from further investigations.

AB - Clinicopathological features, prognosis and therapeutic strategies for mucoepidermoid carcinoma originating in salivary and salivary-type glands of the head and neck are reviewed. We emphasise histopathological aspects, appraise the value of histochemistry, electron microscopy, immunohistochemistry and cytophotometry, and discuss histogenesis and characteristic gene translocations. We additionally consider possible diagnostic difficulties, problems related to histological grading and accuracy of existing literature, and areas of controversy or uncertainty which may benefit from further investigations.

KW - Head and neck

KW - Mucoepidermoid carcinoma

KW - Pathology

KW - Prognosis

KW - Salivary glands

KW - Therapy

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DO - 10.1007/s00405-014-3053-z

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Salivary mucoepidermoid carcinoma revisited

Abstract

Keywords

ASJC Scopus subject areas

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