Abstract
Clinicopathological features, prognosis and therapeutic strategies for mucoepidermoid carcinoma originating in salivary and salivary-type glands of the head and neck are reviewed. We emphasise histopathological aspects, appraise the value of histochemistry, electron microscopy, immunohistochemistry and cytophotometry, and discuss histogenesis and characteristic gene translocations. We additionally consider possible diagnostic difficulties, problems related to histological grading and accuracy of existing literature, and areas of controversy or uncertainty which may benefit from further investigations.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 799-819 |
| Number of pages | 21 |
| Journal | European Archives of Oto-Rhino-Laryngology |
| Volume | 272 |
| Issue number | 4 |
| DOIs | |
| State | Published - 2015 |
Fingerprint
Keywords
- Head and neck
- Mucoepidermoid carcinoma
- Pathology
- Prognosis
- Salivary glands
- Therapy
ASJC Scopus subject areas
- Otorhinolaryngology
- Medicine(all)
Cite this
Salivary mucoepidermoid carcinoma revisited. / Coca-Pelaz, Andrés; Rodrigo, Juan P.; Triantafyllou, Asterios; Hunt, Jennifer L.; Rinaldo, Alessandra; Strojan, Primož; Haigentz, Missak; Mendenhall, William M.; Takes, Robert P.; Vander Poorten, Vincent; Ferlito, Alfio.
In: European Archives of Oto-Rhino-Laryngology, Vol. 272, No. 4, 2015, p. 799-819.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Salivary mucoepidermoid carcinoma revisited
AU - Coca-Pelaz, Andrés
AU - Rodrigo, Juan P.
AU - Triantafyllou, Asterios
AU - Hunt, Jennifer L.
AU - Rinaldo, Alessandra
AU - Strojan, Primož
AU - Haigentz, Missak
AU - Mendenhall, William M.
AU - Takes, Robert P.
AU - Vander Poorten, Vincent
AU - Ferlito, Alfio
PY - 2015
Y1 - 2015
N2 - Clinicopathological features, prognosis and therapeutic strategies for mucoepidermoid carcinoma originating in salivary and salivary-type glands of the head and neck are reviewed. We emphasise histopathological aspects, appraise the value of histochemistry, electron microscopy, immunohistochemistry and cytophotometry, and discuss histogenesis and characteristic gene translocations. We additionally consider possible diagnostic difficulties, problems related to histological grading and accuracy of existing literature, and areas of controversy or uncertainty which may benefit from further investigations.
AB - Clinicopathological features, prognosis and therapeutic strategies for mucoepidermoid carcinoma originating in salivary and salivary-type glands of the head and neck are reviewed. We emphasise histopathological aspects, appraise the value of histochemistry, electron microscopy, immunohistochemistry and cytophotometry, and discuss histogenesis and characteristic gene translocations. We additionally consider possible diagnostic difficulties, problems related to histological grading and accuracy of existing literature, and areas of controversy or uncertainty which may benefit from further investigations.
KW - Head and neck
KW - Mucoepidermoid carcinoma
KW - Pathology
KW - Prognosis
KW - Salivary glands
KW - Therapy
UR - http://www.scopus.com/inward/record.url?scp=84939880495&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84939880495&partnerID=8YFLogxK
U2 - 10.1007/s00405-014-3053-z
DO - 10.1007/s00405-014-3053-z
M3 - Article
C2 - 24771140
AN - SCOPUS:84939880495
VL - 272
SP - 799
EP - 819
JO - Archives of Otolaryngology
JF - Archives of Otolaryngology
SN - 2168-6181
IS - 4
ER -