Abstract
Clinicopathological features, prognosis and therapeutic strategies for mucoepidermoid carcinoma originating in salivary and salivary-type glands of the head and neck are reviewed. We emphasise histopathological aspects, appraise the value of histochemistry, electron microscopy, immunohistochemistry and cytophotometry, and discuss histogenesis and characteristic gene translocations. We additionally consider possible diagnostic difficulties, problems related to histological grading and accuracy of existing literature, and areas of controversy or uncertainty which may benefit from further investigations.
Original language | English (US) |
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Pages (from-to) | 799-819 |
Number of pages | 21 |
Journal | European Archives of Oto-Rhino-Laryngology |
Volume | 272 |
Issue number | 4 |
DOIs | |
State | Published - Apr 2015 |
Keywords
- Head and neck
- Mucoepidermoid carcinoma
- Pathology
- Prognosis
- Salivary glands
- Therapy
ASJC Scopus subject areas
- Otorhinolaryngology