Safety and immunogenicity of the Mycobacterium tuberculosis ΔlysA ΔpanCD vaccine in domestic cats infected with feline immunodeficiency virus

Dawn M. Zimmerman; W. Ray Waters; Konstantin P. Lyashchenko; Brian J. Nonnecke; Douglas L. Armstrong; William R. Jacobs; Michelle H. Larsen; Erin Egan; Gregg A. Dean

doi:10.1128/CVI.00396-08

Safety and immunogenicity of the Mycobacterium tuberculosis ΔlysA ΔpanCD vaccine in domestic cats infected with feline immunodeficiency virus

Dawn M. Zimmerman, W. Ray Waters, Konstantin P. Lyashchenko, Brian J. Nonnecke, Douglas L. Armstrong, William R. Jacobs, Michelle H. Larsen, Erin Egan, Gregg A. Dean

Microbiology & Immunology

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Feline immunodeficiency virus (FIV)-positive and FIV-negative cats (n = 4/group) received 2 × 10⁶ CFU Mycobacterium tuberculosis ΔlysA ΔpanCD intramuscularly. Vaccination elicited antibody responses, albeit at lower levels in FIV-positive cats than in FIV-negative cats. Delayed-type hypersensitivity responses were minimal in both groups. No adverse reactions were found.

Original language	English (US)
Pages (from-to)	427-429
Number of pages	3
Journal	Clinical and Vaccine Immunology
Volume	16
Issue number	3
DOIs	https://doi.org/10.1128/CVI.00396-08
State	Published - Mar 2009

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Clinical Biochemistry
Microbiology (medical)

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10.1128/CVI.00396-08

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Zimmerman, D. M., Waters, W. R., Lyashchenko, K. P., Nonnecke, B. J., Armstrong, D. L., Jacobs, W. R., Larsen, M. H., Egan, E., & Dean, G. A. (2009). Safety and immunogenicity of the Mycobacterium tuberculosis ΔlysA ΔpanCD vaccine in domestic cats infected with feline immunodeficiency virus. Clinical and Vaccine Immunology, 16(3), 427-429. https://doi.org/10.1128/CVI.00396-08

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abstract = "Feline immunodeficiency virus (FIV)-positive and FIV-negative cats (n = 4/group) received 2 × 106 CFU Mycobacterium tuberculosis ΔlysA ΔpanCD intramuscularly. Vaccination elicited antibody responses, albeit at lower levels in FIV-positive cats than in FIV-negative cats. Delayed-type hypersensitivity responses were minimal in both groups. No adverse reactions were found.",

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AU - Zimmerman, Dawn M.

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AU - Lyashchenko, Konstantin P.

AU - Nonnecke, Brian J.

AU - Armstrong, Douglas L.

AU - Jacobs, William R.

AU - Larsen, Michelle H.

AU - Egan, Erin

AU - Dean, Gregg A.

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Safety and immunogenicity of the Mycobacterium tuberculosis ΔlysA ΔpanCD vaccine in domestic cats infected with feline immunodeficiency virus

Abstract

ASJC Scopus subject areas

UN SDGs

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