TY - JOUR
T1 - Safety and effectiveness of transvenous lead extraction in octogenarians
AU - Pelargonio, Gemma
AU - Narducci, Maria L.
AU - Russo, Eleonora
AU - Casella, Michela
AU - Santangeli, Pasquale
AU - Canby, Robert
AU - Al-Ahmad, Amin
AU - Price, Larry D.
AU - Biase, Luigi Di
AU - Kwark, Candice J.
AU - Harwood, Mark
AU - Perna, Francesco
AU - Bencardino, Gianluigi
AU - Ierardi, Carolina
AU - Trecarichi, Enrico M.
AU - Santelli, Enrica
AU - Tumbarello, Mario
AU - Mohanty, Prasant
AU - Bailey, Shane
AU - Burkhardt, John David
AU - Bellocci, Fulvio
AU - Natale, Andrea
AU - Russo, Antonio Dello
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2012/10
Y1 - 2012/10
N2 - Transvenous Lead Extraction. Introduction: As the population ages, the number of elderly patients with implantable cardiac devices referred for transvenous lead extraction will dramatically increase in Western countries. The safety and effectiveness of lead extraction in elderly patients has not been well evaluated. We report the safety and effectiveness of transvenous lead extraction in octogenarians. Methods and Results: From January 2005 to January 2011, we reviewed data from consecutive patients ≥ 80 years referred to our institutions for transvenous lead extraction because of cardiac device infection or lead malfunction. Clinical characteristics, procedural features, and periprocedural major and minor complications were compared between octogenarians and younger patients. Out of 849 patients undergoing lead extraction in the participating institutions during the study period, 150 (18%) patients were octogenarians (mean age 84 years; range 80-96; 64% males). A significantly higher percentage of octogenarians presented with chronic renal failure (55% vs 26%; P < 0.001), history of malignancy (22% vs 6%; P < 0.001), and chronic obstructive pulmonary disease (46% vs 19%; P < 0.001). Complete lead extraction rates were similar in the 2 age groups (97% in octogenarians vs 96% in patients <80 years; P = 0.39). Periprocedural death occurred in 2 (1.3%) patients ≥80 years and in 5 (0.72%) patients <80 years (P = 0.45 for comparison). No differences in terms of other periprocedural major and minor complications were found between the 2 age groups. Conclusion: Despite presenting with a significantly higher rate of comorbidities, transvenous lead extraction can be performed safely and successfully in octogenarians.
AB - Transvenous Lead Extraction. Introduction: As the population ages, the number of elderly patients with implantable cardiac devices referred for transvenous lead extraction will dramatically increase in Western countries. The safety and effectiveness of lead extraction in elderly patients has not been well evaluated. We report the safety and effectiveness of transvenous lead extraction in octogenarians. Methods and Results: From January 2005 to January 2011, we reviewed data from consecutive patients ≥ 80 years referred to our institutions for transvenous lead extraction because of cardiac device infection or lead malfunction. Clinical characteristics, procedural features, and periprocedural major and minor complications were compared between octogenarians and younger patients. Out of 849 patients undergoing lead extraction in the participating institutions during the study period, 150 (18%) patients were octogenarians (mean age 84 years; range 80-96; 64% males). A significantly higher percentage of octogenarians presented with chronic renal failure (55% vs 26%; P < 0.001), history of malignancy (22% vs 6%; P < 0.001), and chronic obstructive pulmonary disease (46% vs 19%; P < 0.001). Complete lead extraction rates were similar in the 2 age groups (97% in octogenarians vs 96% in patients <80 years; P = 0.39). Periprocedural death occurred in 2 (1.3%) patients ≥80 years and in 5 (0.72%) patients <80 years (P = 0.45 for comparison). No differences in terms of other periprocedural major and minor complications were found between the 2 age groups. Conclusion: Despite presenting with a significantly higher rate of comorbidities, transvenous lead extraction can be performed safely and successfully in octogenarians.
KW - elderly
KW - implantable cardioverter defibrillator
KW - infection
KW - lead extraction
KW - octogenarians
KW - pacemaker
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U2 - 10.1111/j.1540-8167.2012.02372.x
DO - 10.1111/j.1540-8167.2012.02372.x
M3 - Article
C2 - 22882701
AN - SCOPUS:84867741186
SN - 1045-3873
VL - 23
SP - 1103
EP - 1108
JO - Journal of cardiovascular electrophysiology
JF - Journal of cardiovascular electrophysiology
IS - 10
ER -