Role of Cytotoxic Therapy with Hematopoietic Cell Transplantation in the Treatment of Hodgkin Lymphoma: Guidelines from the American Society for Blood and Marrow Transplantation

Miguel Angel Perales; Izaskun Ceberio; Philippe Armand; Linda J. Burns; Robert Chen; Peter D. Cole; Andrew M. Evens; Ginna G. Laport; Craig H. Moskowitz; Uday Popat; Nishitha M. Reddy; Thomas C. Shea; Julie M. Vose; Jeffrey Schriber; Bipin N. Savani; Paul A. Carpenter

doi:10.1016/j.bbmt.2015.02.022

Role of Cytotoxic Therapy with Hematopoietic Cell Transplantation in the Treatment of Hodgkin Lymphoma: Guidelines from the American Society for Blood and Marrow Transplantation

Miguel Angel Perales, Izaskun Ceberio, Philippe Armand, Linda J. Burns, Robert Chen, Peter D. Cole, Andrew M. Evens, Ginna G. Laport, Craig H. Moskowitz, Uday Popat, Nishitha M. Reddy, Thomas C. Shea, Julie M. Vose, Jeffrey Schriber, Bipin N. Savani, Paul A. Carpenter

Pediatrics

Research output: Contribution to journal › Review article › peer-review

66 Scopus citations

Abstract

The role of hematopoietic cell transplantation (HCT) in the therapy of Hodgkin lymphoma (HL) in pediatric and adult patients is reviewed and critically evaluated in this systematic evidence-based review. Specific criteria were used for searching the published literature and for grading the quality and strength of the evidence and the strength of the treatment recommendations. Treatment recommendations based on the evidence are included and were reached unanimously by a panel of HL experts. Both autologous and allogeneic HCT offer a survival benefit in selected patients with advanced or relapsed HL and are currently part of standard clinical care. Relapse remains a significant cause of failure after both transplant approaches, and strategies to decrease the risk of relapse remain an important area of investigation.

Original language	English (US)
Pages (from-to)	971-983
Number of pages	13
Journal	Biology of Blood and Marrow Transplantation
Volume	21
Issue number	6
DOIs	https://doi.org/10.1016/j.bbmt.2015.02.022
State	Published - Jun 2015

Keywords

Allogeneic transplant
Autologous transplant
Hematopoietic cell transplantation
Hodgkin lymphoma

ASJC Scopus subject areas

Hematology
Transplantation

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10.1016/j.bbmt.2015.02.022

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Perales, M. A., Ceberio, I., Armand, P., Burns, L. J., Chen, R., Cole, P. D., Evens, A. M., Laport, G. G., Moskowitz, C. H., Popat, U., Reddy, N. M., Shea, T. C., Vose, J. M., Schriber, J., Savani, B. N., & Carpenter, P. A. (2015). Role of Cytotoxic Therapy with Hematopoietic Cell Transplantation in the Treatment of Hodgkin Lymphoma: Guidelines from the American Society for Blood and Marrow Transplantation. Biology of Blood and Marrow Transplantation, 21(6), 971-983. https://doi.org/10.1016/j.bbmt.2015.02.022

Role of Cytotoxic Therapy with Hematopoietic Cell Transplantation in the Treatment of Hodgkin Lymphoma: Guidelines from the American Society for Blood and Marrow Transplantation. / Perales, Miguel Angel; Ceberio, Izaskun; Armand, Philippe et al.
In: Biology of Blood and Marrow Transplantation, Vol. 21, No. 6, 06.2015, p. 971-983.

Research output: Contribution to journal › Review article › peer-review

Perales, MA, Ceberio, I, Armand, P, Burns, LJ, Chen, R, Cole, PD, Evens, AM, Laport, GG, Moskowitz, CH, Popat, U, Reddy, NM, Shea, TC, Vose, JM, Schriber, J, Savani, BN & Carpenter, PA 2015, 'Role of Cytotoxic Therapy with Hematopoietic Cell Transplantation in the Treatment of Hodgkin Lymphoma: Guidelines from the American Society for Blood and Marrow Transplantation', Biology of Blood and Marrow Transplantation, vol. 21, no. 6, pp. 971-983. https://doi.org/10.1016/j.bbmt.2015.02.022

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abstract = "The role of hematopoietic cell transplantation (HCT) in the therapy of Hodgkin lymphoma (HL) in pediatric and adult patients is reviewed and critically evaluated in this systematic evidence-based review. Specific criteria were used for searching the published literature and for grading the quality and strength of the evidence and the strength of the treatment recommendations. Treatment recommendations based on the evidence are included and were reached unanimously by a panel of HL experts. Both autologous and allogeneic HCT offer a survival benefit in selected patients with advanced or relapsed HL and are currently part of standard clinical care. Relapse remains a significant cause of failure after both transplant approaches, and strategies to decrease the risk of relapse remain an important area of investigation.",

keywords = "Allogeneic transplant, Autologous transplant, Hematopoietic cell transplantation, Hodgkin lymphoma",

author = "Perales, {Miguel Angel} and Izaskun Ceberio and Philippe Armand and Burns, {Linda J.} and Robert Chen and Cole, {Peter D.} and Evens, {Andrew M.} and Laport, {Ginna G.} and Moskowitz, {Craig H.} and Uday Popat and Reddy, {Nishitha M.} and Shea, {Thomas C.} and Vose, {Julie M.} and Jeffrey Schriber and Savani, {Bipin N.} and Carpenter, {Paul A.}",

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year = "2015",

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doi = "10.1016/j.bbmt.2015.02.022",

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AU - Armand, Philippe

AU - Burns, Linda J.

AU - Chen, Robert

AU - Cole, Peter D.

AU - Evens, Andrew M.

AU - Laport, Ginna G.

AU - Moskowitz, Craig H.

AU - Popat, Uday

AU - Reddy, Nishitha M.

AU - Shea, Thomas C.

AU - Vose, Julie M.

AU - Schriber, Jeffrey

AU - Savani, Bipin N.

AU - Carpenter, Paul A.

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KW - Allogeneic transplant

KW - Autologous transplant

KW - Hematopoietic cell transplantation

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Role of Cytotoxic Therapy with Hematopoietic Cell Transplantation in the Treatment of Hodgkin Lymphoma: Guidelines from the American Society for Blood and Marrow Transplantation

Abstract

Keywords

ASJC Scopus subject areas

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