@inproceedings{39790c81fb41463c83fc2e72cab739ba,
title = "Role of cavitation in bulk ultrasound ablation: A histologic study",
abstract = "The role of cavitation in bulk ultrasound ablation has been evaluated in a series of in vitro experiments. Fresh bovine liver tissue was ablated with a 3.1 MHz ultrasound image-ablate probe at 31 W/cm 2 for 20 minutes under normal and elevated ambient pressures. A 1 MHz passive cavitation detector recorded acoustic emission signals which were quantified by computation of average subharmonic, broadband, and low-frequency emission levels. After ablation, tissue was sliced and stained with 2% TTC to evaluate thermal damage. Emission levels were quantified and correlated with tissue ablation histology. The results indicate that bubble activity significantly affects heat deposition in ultrasound bulk ablation, in a manner different from high-intensity focused ultrasound (HIFU) ablation.",
keywords = "Bulk ultrasound ablation, Passive cavitation detection, TTC staining",
author = "Karunakaran, {Chandra Priya} and Burgess, {Mark T.} and Holland, {Christy K.} and Mast, {T. Douglas}",
year = "2009",
doi = "10.1063/1.3131467",
language = "English (US)",
isbn = "9780735406506",
series = "AIP Conference Proceedings",
pages = "43--47",
booktitle = "8th International Symposium on Therapeutic Ultrasound",
note = "8th International Symposium on Therapeutic Ultrasound ; Conference date: 10-09-2008 Through 13-09-2008",
}