Abstract
RNA-localization mechansims involve specific sequences in the localized RNA and proteins that bind to these sequences and mediate the interaction with cytoskeletal elements. Until recently, it seemed as thought two separate types of mechanism were operating for mRNA localization - involving interaction with either microtubules or actin microfilaments. However, it is now clear that some of the protein components involved in mRNA localization can participate in both microtubule- and actin-dependent localization pathways. This, combined with new evidence for evolutionary conservation of some of these proteins, suggests a previously unanticipated uniformity in mRNA-localization mechanisms.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 381-383 |
| Number of pages | 3 |
| Journal | Trends in Cell Biology |
| Volume | 8 |
| Issue number | 10 |
| DOIs | |
| State | Published - Oct 1 1998 |
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ASJC Scopus subject areas
- Cell Biology
Cite this
RNA localization : Different zipcodes, same postman? / Oleynikov, Yuri; Singer, Robert H.
In: Trends in Cell Biology, Vol. 8, No. 10, 01.10.1998, p. 381-383.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - RNA localization
T2 - Different zipcodes, same postman?
AU - Oleynikov, Yuri
AU - Singer, Robert H.
PY - 1998/10/1
Y1 - 1998/10/1
N2 - RNA-localization mechansims involve specific sequences in the localized RNA and proteins that bind to these sequences and mediate the interaction with cytoskeletal elements. Until recently, it seemed as thought two separate types of mechanism were operating for mRNA localization - involving interaction with either microtubules or actin microfilaments. However, it is now clear that some of the protein components involved in mRNA localization can participate in both microtubule- and actin-dependent localization pathways. This, combined with new evidence for evolutionary conservation of some of these proteins, suggests a previously unanticipated uniformity in mRNA-localization mechanisms.
AB - RNA-localization mechansims involve specific sequences in the localized RNA and proteins that bind to these sequences and mediate the interaction with cytoskeletal elements. Until recently, it seemed as thought two separate types of mechanism were operating for mRNA localization - involving interaction with either microtubules or actin microfilaments. However, it is now clear that some of the protein components involved in mRNA localization can participate in both microtubule- and actin-dependent localization pathways. This, combined with new evidence for evolutionary conservation of some of these proteins, suggests a previously unanticipated uniformity in mRNA-localization mechanisms.
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UR - http://www.scopus.com/inward/citedby.url?scp=0032190431&partnerID=8YFLogxK
U2 - 10.1016/S0962-8924(98)01348-8
DO - 10.1016/S0962-8924(98)01348-8
M3 - Article
VL - 8
SP - 381
EP - 383
JO - Trends in Cell Biology
JF - Trends in Cell Biology
SN - 0962-8924
IS - 10
ER -