Risperidone-induced reversible neutropenia

Vasanth Kattalai Kailasam; Victoria Chima; Uchechukwu Nnamdi; Kavita Sharma; Kairav Shah

doi:10.2147/NDT.S141472

Risperidone-induced reversible neutropenia

Vasanth Kattalai Kailasam, Victoria Chima, Uchechukwu Nnamdi, Kavita Sharma, Kairav Shah

Psychiatry and Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

This case report presents a 44-year-old man with a history of schizophrenia who developed neutropenia on risperidone therapy. The patient’s laboratory reports showed a gradual decline of leukocytes and neutrophils after resolution and rechallenging. This was reversed with the discontinuation of risperidone and by switching to olanzapine. In this case report, we also discuss the updated evidence base for management of risperidone-induced neutropenia.

Original language	English (US)
Pages (from-to)	1975-1977
Number of pages	3
Journal	Neuropsychiatric Disease and Treatment
Volume	13
DOIs	https://doi.org/10.2147/NDT.S141472
State	Published - Jul 25 2017

Keywords

Antipsychotics
Blood dyscrasias
Neutropenia
Risperidone

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2147/NDT.S141472

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title = "Risperidone-induced reversible neutropenia",

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AU - Kailasam, Vasanth Kattalai

AU - Chima, Victoria

AU - Nnamdi, Uchechukwu

AU - Sharma, Kavita

AU - Shah, Kairav

PY - 2017/7/25

Y1 - 2017/7/25

N2 - This case report presents a 44-year-old man with a history of schizophrenia who developed neutropenia on risperidone therapy. The patient’s laboratory reports showed a gradual decline of leukocytes and neutrophils after resolution and rechallenging. This was reversed with the discontinuation of risperidone and by switching to olanzapine. In this case report, we also discuss the updated evidence base for management of risperidone-induced neutropenia.

AB - This case report presents a 44-year-old man with a history of schizophrenia who developed neutropenia on risperidone therapy. The patient’s laboratory reports showed a gradual decline of leukocytes and neutrophils after resolution and rechallenging. This was reversed with the discontinuation of risperidone and by switching to olanzapine. In this case report, we also discuss the updated evidence base for management of risperidone-induced neutropenia.

KW - Antipsychotics

KW - Blood dyscrasias

KW - Neutropenia

KW - Risperidone

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JO - Neuropsychiatric Disease and Treatment

JF - Neuropsychiatric Disease and Treatment

ER -

Risperidone-induced reversible neutropenia

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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