Risks and benefits of home parenteral nutrition in the acquired immunodeficiency syndrome

P. Singer, M. M. Rothkopf, Vladimir Kvetan, O. Kirvela, J. Gaare, J. Askanazi

Research output: Contribution to journalArticle

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Abstract

The gastrointestinal tract is a major target of the human immunodeficiency virus. Many AIDS patients have weight loss and/or diarrhea. Parenteral nutrition can be used to treat malnutrition associated with malabsorption. We reviewed retrospectively the clinical course of 22 patients with AIDS and weight loss greater than 10% who received home parenteral nutrition (HPN) for 56.2 patient-months. Mean weight loss was 21.4%, mean duration of HPN 2.55 months, mean age 37.4 years. Fifteen patients gained weight, six stabilized and two continued to lose weight. Nine patients returned to previous activity. Five died. The rates of catheter-related sepsis, complications, and metabolic disturbances were 0.12, 0.25, and 0.12/100 catheter days, respectively, results identical to those reported in other patient populations where HPN is commonly applied. We found that HPN induced weight gain and clinical improvement in most patients without higher risks of sepsis than in patients with malignancies.

Original languageEnglish (US)
Pages (from-to)75-79
Number of pages5
JournalJournal of Parenteral and Enteral Nutrition
Volume15
Issue number1
StatePublished - 1991

Fingerprint

Home Parenteral Nutrition
acquired immunodeficiency syndrome
parenteral feeding
Acquired Immunodeficiency Syndrome
Weight Loss
sepsis (infection)
weight loss
catheters
Sepsis
Catheters
Weights and Measures
malabsorption
Parenteral Nutrition
Human immunodeficiency virus
disease course
Malnutrition
malnutrition
Weight Gain
gastrointestinal system
Gastrointestinal Tract

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science

Cite this

Singer, P., Rothkopf, M. M., Kvetan, V., Kirvela, O., Gaare, J., & Askanazi, J. (1991). Risks and benefits of home parenteral nutrition in the acquired immunodeficiency syndrome. Journal of Parenteral and Enteral Nutrition, 15(1), 75-79.

Risks and benefits of home parenteral nutrition in the acquired immunodeficiency syndrome. / Singer, P.; Rothkopf, M. M.; Kvetan, Vladimir; Kirvela, O.; Gaare, J.; Askanazi, J.

In: Journal of Parenteral and Enteral Nutrition, Vol. 15, No. 1, 1991, p. 75-79.

Research output: Contribution to journalArticle

Singer, P, Rothkopf, MM, Kvetan, V, Kirvela, O, Gaare, J & Askanazi, J 1991, 'Risks and benefits of home parenteral nutrition in the acquired immunodeficiency syndrome', Journal of Parenteral and Enteral Nutrition, vol. 15, no. 1, pp. 75-79.
Singer, P. ; Rothkopf, M. M. ; Kvetan, Vladimir ; Kirvela, O. ; Gaare, J. ; Askanazi, J. / Risks and benefits of home parenteral nutrition in the acquired immunodeficiency syndrome. In: Journal of Parenteral and Enteral Nutrition. 1991 ; Vol. 15, No. 1. pp. 75-79.
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