Risk of Ipsilateral Deep Vein Thrombosis After Use of AngioSeal Closure Device in Aneurysmal Subarachnoid Hemorrhage Patients

Aravind Addepalli, Joshua Benton, Shaoyu Zhu, Shira Kaye Mann, Mame P. Fall, Andrew Cox, Muhammed Amir Essibayi, Santiago René Unda, Allan Brook, Seon Kyu Lee, Rafael De La Garza Ramos, David J. Altschul

Research output: Contribution to journalArticle

Abstract

Background: Deep vein thrombosis (DVT) is a known complication in patients with aneurysmal subarachnoid hemorrhage (aSAH). This study investigated the association between use of the AngioSeal (St. Jude Medical, Minnetonka, MN) vascular closure device and the risk of ipsilateral and any DVT event after angiography in patients with aSAH. Methods: We conducted a review of our institutional cerebral angiography database for the years 2005–2018 to identify all adult patients who underwent angiography for aSAH. We compared the incidence of DVT (occurring within 14 days) between aSAH patients who underwent manual compression versus the AngioSeal closure device. Results: A total of 459 aSAH patients underwent angiography; 262 underwent manual compression (57.1%) and 197 received AngioSeal (42.9%). There was a 3.4% rate of ipsilateral DVT in the manual compression group and 7.6% in the AngioSeal closure device group (χ2 test, P = 0.04). Similarly, the rate of any DVT was 8.8% for manual compression and 16.8% for patients who received AngioSeal (χ2 test, P = 0.01). On multivariate analysis, AngioSeal remained a significant independent predictor of ipsilateral DVT (odds ratio 2.4, P = 0.04) and any DVT (odds ratio 2.3, P = 0.01). Conclusions: In aSAH patients undergoing cerebral angiographic procedures with access through the femoral artery, the use of AngioSeal closure device was found to be associated with a significantly increased risk of ipsilateral DVT within 14 days.

Original languageEnglish (US)
JournalWorld Neurosurgery
DOIs
StateAccepted/In press - Jan 1 2019

Fingerprint

Subarachnoid Hemorrhage
Venous Thrombosis
Equipment and Supplies
Angiography
Odds Ratio
Cerebral Angiography
Femoral Artery
Multivariate Analysis
Databases
Incidence

Keywords

  • Aneurysm
  • AngioSeal
  • Closure device
  • Deep vein thrombosis
  • Subarachnoid hemorrhage

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Cite this

Risk of Ipsilateral Deep Vein Thrombosis After Use of AngioSeal Closure Device in Aneurysmal Subarachnoid Hemorrhage Patients. / Addepalli, Aravind; Benton, Joshua; Zhu, Shaoyu; Mann, Shira Kaye; Fall, Mame P.; Cox, Andrew; Essibayi, Muhammed Amir; Unda, Santiago René; Brook, Allan; Lee, Seon Kyu; De La Garza Ramos, Rafael; Altschul, David J.

In: World Neurosurgery, 01.01.2019.

Research output: Contribution to journalArticle

Addepalli, A, Benton, J, Zhu, S, Mann, SK, Fall, MP, Cox, A, Essibayi, MA, Unda, SR, Brook, A, Lee, SK, De La Garza Ramos, R & Altschul, DJ 2019, 'Risk of Ipsilateral Deep Vein Thrombosis After Use of AngioSeal Closure Device in Aneurysmal Subarachnoid Hemorrhage Patients', World Neurosurgery. https://doi.org/10.1016/j.wneu.2019.09.170
Addepalli, Aravind ; Benton, Joshua ; Zhu, Shaoyu ; Mann, Shira Kaye ; Fall, Mame P. ; Cox, Andrew ; Essibayi, Muhammed Amir ; Unda, Santiago René ; Brook, Allan ; Lee, Seon Kyu ; De La Garza Ramos, Rafael ; Altschul, David J. / Risk of Ipsilateral Deep Vein Thrombosis After Use of AngioSeal Closure Device in Aneurysmal Subarachnoid Hemorrhage Patients. In: World Neurosurgery. 2019.
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abstract = "Background: Deep vein thrombosis (DVT) is a known complication in patients with aneurysmal subarachnoid hemorrhage (aSAH). This study investigated the association between use of the AngioSeal (St. Jude Medical, Minnetonka, MN) vascular closure device and the risk of ipsilateral and any DVT event after angiography in patients with aSAH. Methods: We conducted a review of our institutional cerebral angiography database for the years 2005–2018 to identify all adult patients who underwent angiography for aSAH. We compared the incidence of DVT (occurring within 14 days) between aSAH patients who underwent manual compression versus the AngioSeal closure device. Results: A total of 459 aSAH patients underwent angiography; 262 underwent manual compression (57.1{\%}) and 197 received AngioSeal (42.9{\%}). There was a 3.4{\%} rate of ipsilateral DVT in the manual compression group and 7.6{\%} in the AngioSeal closure device group (χ2 test, P = 0.04). Similarly, the rate of any DVT was 8.8{\%} for manual compression and 16.8{\%} for patients who received AngioSeal (χ2 test, P = 0.01). On multivariate analysis, AngioSeal remained a significant independent predictor of ipsilateral DVT (odds ratio 2.4, P = 0.04) and any DVT (odds ratio 2.3, P = 0.01). Conclusions: In aSAH patients undergoing cerebral angiographic procedures with access through the femoral artery, the use of AngioSeal closure device was found to be associated with a significantly increased risk of ipsilateral DVT within 14 days.",
keywords = "Aneurysm, AngioSeal, Closure device, Deep vein thrombosis, Subarachnoid hemorrhage",
author = "Aravind Addepalli and Joshua Benton and Shaoyu Zhu and Mann, {Shira Kaye} and Fall, {Mame P.} and Andrew Cox and Essibayi, {Muhammed Amir} and Unda, {Santiago Ren{\'e}} and Allan Brook and Lee, {Seon Kyu} and {De La Garza Ramos}, Rafael and Altschul, {David J.}",
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T1 - Risk of Ipsilateral Deep Vein Thrombosis After Use of AngioSeal Closure Device in Aneurysmal Subarachnoid Hemorrhage Patients

AU - Addepalli, Aravind

AU - Benton, Joshua

AU - Zhu, Shaoyu

AU - Mann, Shira Kaye

AU - Fall, Mame P.

AU - Cox, Andrew

AU - Essibayi, Muhammed Amir

AU - Unda, Santiago René

AU - Brook, Allan

AU - Lee, Seon Kyu

AU - De La Garza Ramos, Rafael

AU - Altschul, David J.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Background: Deep vein thrombosis (DVT) is a known complication in patients with aneurysmal subarachnoid hemorrhage (aSAH). This study investigated the association between use of the AngioSeal (St. Jude Medical, Minnetonka, MN) vascular closure device and the risk of ipsilateral and any DVT event after angiography in patients with aSAH. Methods: We conducted a review of our institutional cerebral angiography database for the years 2005–2018 to identify all adult patients who underwent angiography for aSAH. We compared the incidence of DVT (occurring within 14 days) between aSAH patients who underwent manual compression versus the AngioSeal closure device. Results: A total of 459 aSAH patients underwent angiography; 262 underwent manual compression (57.1%) and 197 received AngioSeal (42.9%). There was a 3.4% rate of ipsilateral DVT in the manual compression group and 7.6% in the AngioSeal closure device group (χ2 test, P = 0.04). Similarly, the rate of any DVT was 8.8% for manual compression and 16.8% for patients who received AngioSeal (χ2 test, P = 0.01). On multivariate analysis, AngioSeal remained a significant independent predictor of ipsilateral DVT (odds ratio 2.4, P = 0.04) and any DVT (odds ratio 2.3, P = 0.01). Conclusions: In aSAH patients undergoing cerebral angiographic procedures with access through the femoral artery, the use of AngioSeal closure device was found to be associated with a significantly increased risk of ipsilateral DVT within 14 days.

AB - Background: Deep vein thrombosis (DVT) is a known complication in patients with aneurysmal subarachnoid hemorrhage (aSAH). This study investigated the association between use of the AngioSeal (St. Jude Medical, Minnetonka, MN) vascular closure device and the risk of ipsilateral and any DVT event after angiography in patients with aSAH. Methods: We conducted a review of our institutional cerebral angiography database for the years 2005–2018 to identify all adult patients who underwent angiography for aSAH. We compared the incidence of DVT (occurring within 14 days) between aSAH patients who underwent manual compression versus the AngioSeal closure device. Results: A total of 459 aSAH patients underwent angiography; 262 underwent manual compression (57.1%) and 197 received AngioSeal (42.9%). There was a 3.4% rate of ipsilateral DVT in the manual compression group and 7.6% in the AngioSeal closure device group (χ2 test, P = 0.04). Similarly, the rate of any DVT was 8.8% for manual compression and 16.8% for patients who received AngioSeal (χ2 test, P = 0.01). On multivariate analysis, AngioSeal remained a significant independent predictor of ipsilateral DVT (odds ratio 2.4, P = 0.04) and any DVT (odds ratio 2.3, P = 0.01). Conclusions: In aSAH patients undergoing cerebral angiographic procedures with access through the femoral artery, the use of AngioSeal closure device was found to be associated with a significantly increased risk of ipsilateral DVT within 14 days.

KW - Aneurysm

KW - AngioSeal

KW - Closure device

KW - Deep vein thrombosis

KW - Subarachnoid hemorrhage

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