Risk of bladder cancer by source and type of tobacco exposure: A case-control study

J. D. Burch, Thomas E. Rohan, G. R. Howe, H. A. Risch, G. B. Hill, R. Steele, A. B. Miller

Research output: Contribution to journalArticle

151 Citations (Scopus)

Abstract

The association between tobacco use and risk of bladder cancer was investigated in a population-based case-control study conducted in Alberta and south-central Ontario, Canada, between 1979 and 1982. In all, 826 histologically-confirmed cancer cases and 792 randomly selected controls, individually matched to cases for age, sex, and area of residence were recruited into the study. Compared to those who had never smoked cigarettes had a statistically highly significant 2-fold increase in risk of bladder cancer; for ex-smokers, the risk was intermediate between that for current smokers and never-smokers. There was a dose-dependent increase in risk of bladder cancer with total lifetime cigarette consumption, of similar magnitude for males and females. In males, risk increased with self-reported degree of inhalation in ex-smokers and in current smokers (statistically significant trend), while in females there was no association in current smokers, and a statistically significant inverse association in ex-smokers. Overall, risks of bladder cancer associated with lifetime consumption of plain and filter cigarettes were similar, and there was little evidence to suggest that switching from plain to filter cigarettes was beneficial. Neither passive smoking nor other forms of tobacco consumption (pipes, cigars, chewing tobacco, or snuff) were associated with altered risk of bladder cancer. The population attributable risk for cigarrete smoking was about 47% in males and about 33% in females.

Original languageEnglish (US)
Pages (from-to)622-628
Number of pages7
JournalInternational Journal of Cancer
Volume44
Issue number4
StatePublished - 1989
Externally publishedYes

Fingerprint

Urinary Bladder Neoplasms
Tobacco
Case-Control Studies
Tobacco Products
Smokeless Tobacco
Tobacco Use
Alberta
Tobacco Smoke Pollution
Ontario
Inhalation
Population
Canada
Smoking
Neoplasms

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Burch, J. D., Rohan, T. E., Howe, G. R., Risch, H. A., Hill, G. B., Steele, R., & Miller, A. B. (1989). Risk of bladder cancer by source and type of tobacco exposure: A case-control study. International Journal of Cancer, 44(4), 622-628.

Risk of bladder cancer by source and type of tobacco exposure : A case-control study. / Burch, J. D.; Rohan, Thomas E.; Howe, G. R.; Risch, H. A.; Hill, G. B.; Steele, R.; Miller, A. B.

In: International Journal of Cancer, Vol. 44, No. 4, 1989, p. 622-628.

Research output: Contribution to journalArticle

Burch, JD, Rohan, TE, Howe, GR, Risch, HA, Hill, GB, Steele, R & Miller, AB 1989, 'Risk of bladder cancer by source and type of tobacco exposure: A case-control study', International Journal of Cancer, vol. 44, no. 4, pp. 622-628.
Burch, J. D. ; Rohan, Thomas E. ; Howe, G. R. ; Risch, H. A. ; Hill, G. B. ; Steele, R. ; Miller, A. B. / Risk of bladder cancer by source and type of tobacco exposure : A case-control study. In: International Journal of Cancer. 1989 ; Vol. 44, No. 4. pp. 622-628.
@article{19481c8754c048519f75602aa6349d2c,
title = "Risk of bladder cancer by source and type of tobacco exposure: A case-control study",
abstract = "The association between tobacco use and risk of bladder cancer was investigated in a population-based case-control study conducted in Alberta and south-central Ontario, Canada, between 1979 and 1982. In all, 826 histologically-confirmed cancer cases and 792 randomly selected controls, individually matched to cases for age, sex, and area of residence were recruited into the study. Compared to those who had never smoked cigarettes had a statistically highly significant 2-fold increase in risk of bladder cancer; for ex-smokers, the risk was intermediate between that for current smokers and never-smokers. There was a dose-dependent increase in risk of bladder cancer with total lifetime cigarette consumption, of similar magnitude for males and females. In males, risk increased with self-reported degree of inhalation in ex-smokers and in current smokers (statistically significant trend), while in females there was no association in current smokers, and a statistically significant inverse association in ex-smokers. Overall, risks of bladder cancer associated with lifetime consumption of plain and filter cigarettes were similar, and there was little evidence to suggest that switching from plain to filter cigarettes was beneficial. Neither passive smoking nor other forms of tobacco consumption (pipes, cigars, chewing tobacco, or snuff) were associated with altered risk of bladder cancer. The population attributable risk for cigarrete smoking was about 47{\%} in males and about 33{\%} in females.",
author = "Burch, {J. D.} and Rohan, {Thomas E.} and Howe, {G. R.} and Risch, {H. A.} and Hill, {G. B.} and R. Steele and Miller, {A. B.}",
year = "1989",
language = "English (US)",
volume = "44",
pages = "622--628",
journal = "International Journal of Cancer",
issn = "0020-7136",
publisher = "Wiley-Liss Inc.",
number = "4",

}

TY - JOUR

T1 - Risk of bladder cancer by source and type of tobacco exposure

T2 - A case-control study

AU - Burch, J. D.

AU - Rohan, Thomas E.

AU - Howe, G. R.

AU - Risch, H. A.

AU - Hill, G. B.

AU - Steele, R.

AU - Miller, A. B.

PY - 1989

Y1 - 1989

N2 - The association between tobacco use and risk of bladder cancer was investigated in a population-based case-control study conducted in Alberta and south-central Ontario, Canada, between 1979 and 1982. In all, 826 histologically-confirmed cancer cases and 792 randomly selected controls, individually matched to cases for age, sex, and area of residence were recruited into the study. Compared to those who had never smoked cigarettes had a statistically highly significant 2-fold increase in risk of bladder cancer; for ex-smokers, the risk was intermediate between that for current smokers and never-smokers. There was a dose-dependent increase in risk of bladder cancer with total lifetime cigarette consumption, of similar magnitude for males and females. In males, risk increased with self-reported degree of inhalation in ex-smokers and in current smokers (statistically significant trend), while in females there was no association in current smokers, and a statistically significant inverse association in ex-smokers. Overall, risks of bladder cancer associated with lifetime consumption of plain and filter cigarettes were similar, and there was little evidence to suggest that switching from plain to filter cigarettes was beneficial. Neither passive smoking nor other forms of tobacco consumption (pipes, cigars, chewing tobacco, or snuff) were associated with altered risk of bladder cancer. The population attributable risk for cigarrete smoking was about 47% in males and about 33% in females.

AB - The association between tobacco use and risk of bladder cancer was investigated in a population-based case-control study conducted in Alberta and south-central Ontario, Canada, between 1979 and 1982. In all, 826 histologically-confirmed cancer cases and 792 randomly selected controls, individually matched to cases for age, sex, and area of residence were recruited into the study. Compared to those who had never smoked cigarettes had a statistically highly significant 2-fold increase in risk of bladder cancer; for ex-smokers, the risk was intermediate between that for current smokers and never-smokers. There was a dose-dependent increase in risk of bladder cancer with total lifetime cigarette consumption, of similar magnitude for males and females. In males, risk increased with self-reported degree of inhalation in ex-smokers and in current smokers (statistically significant trend), while in females there was no association in current smokers, and a statistically significant inverse association in ex-smokers. Overall, risks of bladder cancer associated with lifetime consumption of plain and filter cigarettes were similar, and there was little evidence to suggest that switching from plain to filter cigarettes was beneficial. Neither passive smoking nor other forms of tobacco consumption (pipes, cigars, chewing tobacco, or snuff) were associated with altered risk of bladder cancer. The population attributable risk for cigarrete smoking was about 47% in males and about 33% in females.

UR - http://www.scopus.com/inward/record.url?scp=0024420537&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024420537&partnerID=8YFLogxK

M3 - Article

C2 - 2793235

AN - SCOPUS:0024420537

VL - 44

SP - 622

EP - 628

JO - International Journal of Cancer

JF - International Journal of Cancer

SN - 0020-7136

IS - 4

ER -