Risk factor scoring for predicting venous thromboembolism in obstetric patients

Nofit Weiss, Peter S. Bernstein

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

OBJECTIVE: The aim of this study was to develop a risk factor scoring system for the prediction of venous thromboembolism in obstetric patients. STUDY DESIGN: We conducted a retrospective case-control study of all pregnant or postpartum women admitted to the Jack D. Weiler Hospital from 1987 through 1998 with a discharge diagnosis indicating thromboembolism. For each study subject the three women who were delivered immediately before that index patient were selected for the control group. Data collected included the following: history of thrombosis, age, body mass index, previous abdominal surgical procedures; presence of systemic diseases, and blood type. Each patient was assigned a score that was based on the risk factors identified. RESULTS: We identified 21 patients who had sustained thromboembolic events during pregnancy or 6 weeks post partum. Nineteen of the thromboembolic events (90%) were diagnosed during pregnancy, and these cases were distributed throughout gestation - 8 (42%) in the first trimester, 2 (10%) in the second trimester, and 9 (48%) in the third trimester. Six (28%) of these patients had pulmonary embolisms. Two cases of postpartum thromboembolic events were documented. Both were cases of pulmonary embolism. There was 1 maternal death. Patients with a score >2 were at significantly increased risk for having a thromboembolism, with an odds ratio of 4.8 (P < .05). The sensitivity, specificity, positive predictive value, and negative predictive value of this cutoff point were 21%, 95%, 57%; and 78%, respectively. CONCLUSION: Obstetric patients with high risk factor scores were at increased risk for thromboembolism.

Original languageEnglish (US)
Pages (from-to)1073-1075
Number of pages3
JournalAmerican Journal of Obstetrics and Gynecology
Volume182
Issue number5
DOIs
StatePublished - 2000

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Venous Thromboembolism
Obstetrics
Thromboembolism
Pulmonary Embolism
Pregnancy
Postpartum Period
Maternal Death
Hematologic Diseases
Third Pregnancy Trimester
Second Pregnancy Trimester
First Pregnancy Trimester
Case-Control Studies
Pregnant Women
Body Mass Index
Thrombosis
Odds Ratio
Sensitivity and Specificity
Control Groups

Keywords

  • Deep vein thrombosis
  • Pregnancy
  • Pulmonary embolism
  • Risk factor scoring
  • Thromboembolism

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Risk factor scoring for predicting venous thromboembolism in obstetric patients. / Weiss, Nofit; Bernstein, Peter S.

In: American Journal of Obstetrics and Gynecology, Vol. 182, No. 5, 2000, p. 1073-1075.

Research output: Contribution to journalArticle

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