Rhabdomyolysis and AKI with Atorvastatin and Sitagliptin Use in the Setting of Low 25-Hydroxyvitamin D Levels

Rupinder Singh Buttar, Jasveen Batra, Jacqueline Kreimerman, Melissa Aleta, Michal L. Melamed

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

We report a case of an 86-year-old woman admitted to the hospital with rhabdomyolysis and acute kidney injury 3 weeks after starting sitagliptin while on long-term atorvastatin therapy. She also had low levels of 25-hydroxyvitamin D and mild chronic kidney disease, which may have contributed to the development of rhabdomyolysis. A review of the literature reveals four previous reports of this drug interaction in elderly patients, some with underlying kidney disease.

Original languageEnglish (US)
Pages (from-to)1156-1159
Number of pages4
JournalJournal of general internal medicine
Volume32
Issue number10
DOIs
StatePublished - Oct 1 2017

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Keywords

  • acute kidney injury
  • drug interaction
  • rhabdomyolysis
  • sitagliptin
  • statins
  • vitamin D

ASJC Scopus subject areas

  • Internal Medicine

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