Retinopatia tipo Purtscher em paciente com coagulopatia associada ao COVID-19

Translated title of the contribution: Purtscher-like retinopathy in a patient with COVID-19-associated coagulopathy

Joyce N. Mbekeani, Nilesh K. Raval, Thomas A. Vo, Irene M. Rusu, Sophie Zhirong Lin, Christine M. Coyle, Julie P. Hoffman

Research output: Contribution to journalLetterpeer-review


The most frequently reported ophthalmic manifestation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is conjunctivitis. We have described a case of Purtscher-like retinopathy in a patient with severe coronavirus disease 2019 (COVID-19)-associated coagulopathy. A young woman with multiple comorbidities was admitted for COVID-19-related acute respiratory distress syndrome. Her course was complicated by fungemia. Ophthalmic examination revealed bilateral posterior pole, intraretinal lesions and fluconazole was added for presumed fungal retinitis. At 1-week follow-up, widespread peripapillary cotton-wool spots and hemorrhages suggestive of Purtscher-like retinopathy were observed. The levels of D-dimers, fibrinogen, and C-reactive protein were markedly elevated prior to our consultation, indicating preceding prothrombotic and pro-inflammatory states. Subsequent venous duplex revealed deep venous thrombosis in the right subclavian and internal jugular veins. Von Willebrand factor indices were markedly elevated, suggesting severe COVID-19-associated coagulopathy. Purtscher-like retinopathy, a rare occlusive microangiopathy has been described in various pro-inflammatory and prothrombotic conditions. To the best of our knowledge, this is the first report of Purtscher-like retinopathy in COVID-19-associated coagulopathy.

Translated title of the contributionPurtscher-like retinopathy in a patient with COVID-19-associated coagulopathy
Original languagePortuguese
JournalArquivos Brasileiros de Oftalmologia
Issue number4
StatePublished - 2022


  • Case report
  • Coronavirus infection
  • Retinal disease
  • Severe acute respiratory syndrome

ASJC Scopus subject areas

  • Ophthalmology


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