Rethinking the use of auditory brainstem response in acoustic neuroma screening

John J. Zappia, Cathleen A. O'Connor, Richard J. Wiet, Elizabeth A. Dinces

Research output: Contribution to journalArticlepeer-review

40 Scopus citations


The ability of magnetic resonance imaging (MRI) to detect very small acoustic tumors has triggered many to rethink the use of auditory brain-stem response (ABR) in the screening of acoustic tumors. To assess ABR accuracy, we conducted a retrospective study of 388 surgically treated patients. Of these patients, 111 had complete data-bases including both preoperative MRIs and ABRs. The ABR was abnormal by wave V interaural latency difference in 106 (95%) of the cases. Although our overall sensitivity was 95%, sensitivity varied according to tumor size. ABR was abnormal or absent for all tumors (100%) larger than 2 cm in diameter, for 98% of tumors 1.1 to 2 cm in diameter, and for only 89% of tumors less than or equal to 1 cm in diameter. Ramifications of this in the decision-making process are presented. Criteria for cut-off values are also discussed.

Original languageEnglish (US)
Pages (from-to)1388-1392
Number of pages5
Issue number10
StatePublished - Oct 1 1997
Externally publishedYes

ASJC Scopus subject areas

  • Otorhinolaryngology


Dive into the research topics of 'Rethinking the use of auditory brainstem response in acoustic neuroma screening'. Together they form a unique fingerprint.

Cite this