Results of soy-based meal replacement formula on weight, anthropometry, serum lipids & blood pressure during a 40-week clinical weight loss trial

Kevin R. Fontaine, Dongyan Yang, Gary L. Gadbury, Stanley Heshka, Linda G. Schwartz, Radha Murugesan, Jennifer L. Kraker, Moonseong Heo, Steven B. Heymsfield, David B. Allison

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Background: To evaluate the intermediate-term health outcomes associated with a soy-based meal replacement, and to compare the weight loss efficacy of two distinct patterns of caloric restriction. Methods: Ninety overweight/obese (28 < BMI ≤ 41 kg/m2) adults received a single session of dietary counseling and were randomized to either 12 weeks at 1200 kcal/day, 16 weeks at 1500 kcal/d and 12 weeks at 1800 kcal/d (i.e., the 12/15/18 diet group), or 28 weeks at 1500 kcal/d and 12 weeks at 1800 kcal/d (i.e., the 15/18 diet group). Weight, body fat, waist circumference, blood pressure and serum lipid concentrations were measured at 4-week intervals throughout the 40-week trial. Results: Subjects in both treatments showed statistically significant improvements in outcomes. A regression model for weight change suggests that subjects with larger baseline weights tended to lose more weight and subjects in the 12/15/18 group tended to experience, on average, an additional 0.9 kg of weight loss compared with subjects in the 15/18 group. Conclusion: Both treatments using the soy-based meal replacement program were associated with significant and comparable weight loss and improvements on selected health variables.

Original languageEnglish (US)
Article number1
Pages (from-to)1-7
Number of pages7
JournalNutrition Journal
Volume2
DOIs
StatePublished - Nov 18 2003

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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    Fontaine, K. R., Yang, D., Gadbury, G. L., Heshka, S., Schwartz, L. G., Murugesan, R., Kraker, J. L., Heo, M., Heymsfield, S. B., & Allison, D. B. (2003). Results of soy-based meal replacement formula on weight, anthropometry, serum lipids & blood pressure during a 40-week clinical weight loss trial. Nutrition Journal, 2, 1-7. [1]. https://doi.org/10.1186/1475-2891-2-14