Abstract
Specific messenger RNAs (mRNAs) can be sequestered within distinct cellular locations, but little is known about how this is accomplished. The participation of the three major cellular filaments in the localization of actin mRNA was studied in chicken embryo fibroblasts. Movement of actin mRNA to the cell periphery and maintenance of that regionalization required intact microfilaments (composed of actin) but not microtubules or intermediate filaments. The results presented here suggest that actin-binding proteins may participate in mRNA sorting.
Original language | English (US) |
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Pages (from-to) | 1275-1277 |
Number of pages | 3 |
Journal | Science |
Volume | 253 |
Issue number | 5025 |
State | Published - Sep 13 1991 |
Externally published | Yes |
ASJC Scopus subject areas
- General