Renal Function Recovery in Chronic Dialysis Patients

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Renal function recovery (RFR) from acute kidney injury requiring dialysis occurs at a high frequency. RFR from chronic dialysis, on the other hand, is an uncommon but well-recognized phenomenon, occurring at a rate of 1.0-2.4% according to data from large observational studies. The underlying etiology of renal failure is the single most important predicting factor of RFR in chronic dialysis patients. The disease types with the highest RFR rates are atheroembolic renal disease, systemic autoimmune disease, renovascular diseases, and scleroderma. The disease types with the lowest RFR rates are diabetic nephropathy and cystic kidney disease. Initial dialysis modality does not appear to influence RFR. Careful observation and history taking are needed to recognize the often nonspecific clinical and laboratory signs of RFR. When RFR is suspected in a chronic dialysis patient, a 24-hour urine urea and creatinine clearance should be measured. Based on the renal clearance, along with other clinical factors, the dialysis prescription may be gradually reduced until a complete discontinuation of dialysis. After RFR from maintenance dialysis, patients require close follow-up in an office setting for chronic kidney disease management.

Original languageEnglish (US)
Pages (from-to)606-613
Number of pages8
JournalSeminars in Dialysis
Volume23
Issue number6
DOIs
StatePublished - Nov 2010

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Recovery of Function
Dialysis
Kidney
Diabetic Nephropathies
Cystic Kidney Diseases
Disease Management
Chronic Renal Insufficiency
Acute Kidney Injury
Autoimmune Diseases
Observational Studies
Renal Insufficiency
Prescriptions
Urea
Creatinine
Maintenance
Observation
Urine

ASJC Scopus subject areas

  • Nephrology

Cite this

Renal Function Recovery in Chronic Dialysis Patients. / Chu, Jay K.; Folkert, Vaughn Wesley.

In: Seminars in Dialysis, Vol. 23, No. 6, 11.2010, p. 606-613.

Research output: Contribution to journalArticle

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