Nierenfunktion nach wiederholter Katheterablation bei lange bestehendem persistierendem Vorhofflimmern: Vorhersage verbesserter Nierenfunktion durch niedrigen CHA2DS2-VASc-Score und Sinusrhythmus

Translated title of the contribution: Renal function after repeat catheter ablation for long-standing persistent atrial fibrillation: Low CHA2DS2-VASc score and sinus rhythm predict improved renal function

Q. Wang, X. D. Zhang, X. Liu, Y. Q. Yang

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Background: Renal impairment and atrial fibrillation (AF) often coexist. Catheter ablation is an effective way to reduce the burden of AF and improve symptoms; however, little is known about the relationship between renal function and AF and its role in the progression of AF for patients undergoing repeat catheter ablation. Methods: In all, 171 patients with long-standing persistent AF ablation were enrolled in the study. The patients were divided into two groups according to their delta estimated glomerular filtration rate (eGFR) values, which was defined as the eGFR before the repeat procedure minus the eGFR before the initial procedure. Patients with decreasing eGFR (delta eGFR < 0) were categorized as group I, while individuals with no change or increasing eGFR (delta eGFR≥ 0) were categorized as group II. eGFR was estimated at baseline and at the 12-month and 24-month follow-up visits. Results: After a mean follow-up of 31.4 ± 13.2 months, group I had a significantly higher arrhythmia recurrence rate than group II (71.2 vs. 49.2 %, p < 0.001). On multivariable analyses, eGFR changes after the repeat procedure were associated with arrhythmia recurrence, hypertrophic cardiomyopathy, and CHA2DS2-VASc score. Patients with arrhythmia recurrence and those with a CHA2DS2-VASc score of ≥ 3 were more likely to show an eGFR decline at follow-up. Conclusion: Patients with long-standing persistent AF, with a failed initial ablation procedure and undergoing a repeat ablation procedure, appear to have a higher risk of arrhythmia recurrence. During the follow-up period, patients without arrhythmia recurrence and those with a CHA2DS2-VASc score of < 3 show improved renal function.

Translated title of the contributionRenal function after repeat catheter ablation for long-standing persistent atrial fibrillation: Low CHA2DS2-VASc score and sinus rhythm predict improved renal function
Original languageGerman
Pages (from-to)331-341
Number of pages11
JournalHerz
Volume41
Issue number4
DOIs
StatePublished - Jun 1 2016
Externally publishedYes

Keywords

  • Atrial fibrillation
  • CHADS-VASc score
  • Estimated glomerular filtration rate
  • Renal function
  • Repeat catheter ablation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint

Dive into the research topics of 'Renal function after repeat catheter ablation for long-standing persistent atrial fibrillation: Low CHA<sub>2</sub>DS<sub>2</sub>-VASc score and sinus rhythm predict improved renal function'. Together they form a unique fingerprint.

Cite this