Objective To assess significance of focal FDG uptake in osseous structures, with and without CT correlate, in patients undergoing FDG PET/CT for oncological indications. Methods 57 patients with focally increased FDG activity in bones and a definite follow up were included. Results 85.2% of lesions without changes were found to be malignant. Sensitivity and PPV of a CT correlate in metastatic lesions was expectedly high, 62.9% and 86.7% respectively, however, the NPV was only 14.8%. Conclusion Osseous foci are valuable in predicting metastatic disease even in the absence of low dose CT correlate.
- Bone metastases
- CT correlate
- FDG PET
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging