Relevance of focal osseous uptake on FDG PET with or without CT changes in oncology patients

Gunjan Garg, Raphaella DaSilva, Mimi Kim, Charito Love, Tony Abraham

Research output: Contribution to journalArticle


Objective To assess significance of focal FDG uptake in osseous structures, with and without CT correlate, in patients undergoing FDG PET/CT for oncological indications. Methods 57 patients with focally increased FDG activity in bones and a definite follow up were included. Results 85.2% of lesions without changes were found to be malignant. Sensitivity and PPV of a CT correlate in metastatic lesions was expectedly high, 62.9% and 86.7% respectively, however, the NPV was only 14.8%. Conclusion Osseous foci are valuable in predicting metastatic disease even in the absence of low dose CT correlate.

Original languageEnglish (US)
Pages (from-to)138-146
Number of pages9
JournalClinical Imaging
StatePublished - Mar 1 2017



  • Bone metastases
  • CT correlate

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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