Relation of gender to physician use of test results and to the prognostic value of stress technetium 99m sestamibi myocardial single-photon emission computed tomography scintigraphy

M. I. Travin, M. D. Duca, G. M. Kline, S. D. Herman, D. D. Demus, G. V. Heller

Research output: Contribution to journalArticle

47 Scopus citations


We analyzed potential gender differences in the use and prognostic value of stress technetium 99m sestamibi tomography, image results, and cardiac event rates over a period of 15 ± 8 months in 1226 men and 1151 women. Men had more abnormal tomographic images, but referral for catheterization and revascularization similarly increased in relation to the number of defects. Men and women with abnormal images had similar event rates, 19.6% and 18.2%, resaectively, although men more often had myocardial infarction or cardiac death (7.6% vs 4.1%, p < 0.05), whereas women had an increased likelihood of unstable angina or congestive heart failure (11.5% vs 7.6%, p < 0.05). Normal images predicted a low yearly rate of myocardial infarction or death: 1.7% for men and 0.8% for women. Image findings, particularly defect extent, were independent predictors of events in both groups. Thus, after stress Tc-99m sestamibi single-photon emission computed tomography perfusion imaging, there was no gender bias in referral for invasive procedures, and for both men and women image findings were strongly associated with prognostic outcome.

Original languageEnglish (US)
Pages (from-to)73-82
Number of pages10
JournalAmerican heart journal
Issue number1
StatePublished - Jan 1 1997
Externally publishedYes


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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