TY - JOUR
T1 - Regional variation in ICU care for pediatric patients with asthma
AU - Bratton, Susan L.
AU - Odetola, Folafoluwa O.
AU - McCollegan, Jamie
AU - Cabana, Michael D.
AU - Levy, Fiona H.
AU - Keenan, Heather T.
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2005/9
Y1 - 2005/9
N2 - Objective: To determine adherence to guidelines for severe asthma care and evaluate regional variability in practice among pediatric intensive care units (PICU). Study design: A retrospective cohort study of children treated for asthma in a PICU during 2000 to 2003. We utilized the Pediatric Health Information System (PHIS) database to identify patients and determine use of asthma therapies when patients did not improve with standard therapy (inhaled β-agonists and systemic corticosteroids). Results: Of 7125 children studied, 59% received inhaled anticholinergic medications. Use of other therapies included systemic β-agonists (n = 1841 [26%]), magnesium sulfate (n = 1521 [21%]), methylxanthines (n = 426 [6%]), inhaled helium-oxigen gas mixture (heliox) (n = 740 [10%]), and endotracheal intubation with ventilation (n = 1024 [14%]). Use of therapies varied by census region. Over half the patients (n = 524) who received ventilation did so for ≤1 day. Adjusted for severity of illness, use of mechanical ventilation varied significantly by census division; however, much of the variation was among children ventilated for ≤1 day. Conclusion: Adherence to national guidelines for use of inhaled anticholinergics among critically ill children is low, and marked variation in use of invasive ventilation exists. More explicit guidelines regarding indications for invasive ventilation may improve asthma care.
AB - Objective: To determine adherence to guidelines for severe asthma care and evaluate regional variability in practice among pediatric intensive care units (PICU). Study design: A retrospective cohort study of children treated for asthma in a PICU during 2000 to 2003. We utilized the Pediatric Health Information System (PHIS) database to identify patients and determine use of asthma therapies when patients did not improve with standard therapy (inhaled β-agonists and systemic corticosteroids). Results: Of 7125 children studied, 59% received inhaled anticholinergic medications. Use of other therapies included systemic β-agonists (n = 1841 [26%]), magnesium sulfate (n = 1521 [21%]), methylxanthines (n = 426 [6%]), inhaled helium-oxigen gas mixture (heliox) (n = 740 [10%]), and endotracheal intubation with ventilation (n = 1024 [14%]). Use of therapies varied by census region. Over half the patients (n = 524) who received ventilation did so for ≤1 day. Adjusted for severity of illness, use of mechanical ventilation varied significantly by census division; however, much of the variation was among children ventilated for ≤1 day. Conclusion: Adherence to national guidelines for use of inhaled anticholinergics among critically ill children is low, and marked variation in use of invasive ventilation exists. More explicit guidelines regarding indications for invasive ventilation may improve asthma care.
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U2 - 10.1016/j.jpeds.2005.05.008
DO - 10.1016/j.jpeds.2005.05.008
M3 - Article
C2 - 16182675
AN - SCOPUS:25144454655
SN - 0022-3476
VL - 147
SP - 355
EP - 361
JO - Journal of Pediatrics
JF - Journal of Pediatrics
IS - 3
ER -