Reduced-representation methylation mapping

Jeffrey A. Jeddeloh, John M. Greally, Oliver J. Rando

Research output: Contribution to journalShort survey

20 Scopus citations

Abstract

The power of massively parallel sequencing has been harnessed to map cytosine methylation patterns in the mouse genome, allowing insights into the relationship of methylation with DNA sequence, histone modifications, transcriptional activity and dynamic changes in methylation status during differentiation.

Original languageEnglish (US)
Article number231
JournalGenome biology
Volume9
Issue number8
DOIs
StatePublished - Sep 1 2008

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Genetics
  • Cell Biology

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