Recurrent Hyperparathyroidism from an Autotransplanted Parathyroid Adenoma

Murray F. Brennan, Edward M. Brown, Stephen J. Marx, Allen M. Spiegel, Arthur E. Broadus, John L. Doppman, Bruce Webber, Gerald D. Aurbach

Research output: Contribution to journalArticle

39 Scopus citations

Abstract

AUTOTRANSPLANTATION of human parathyroid tissue into the forearm prevents hypoparathyroidism after total removal of parathyroid tissue from the neck.12 This procedure has been principally applied at the time of first operation in patients with hyperparathyroidism secondary to chronic renal failure. Since the secondarily hyperplastic cells presumably retain normal functional capacity, a small autograft can restore approximately normal mineral homeostasis.1 2 3 4 This procedure could be applied to all forms of parathyroid hyperplasia,1 although concern has been expressed about the possible risk of recurrent or persistent disease.5 This report illustrates one possible long-term complication of autotransplantation using tissue with abnormal cellular function. We.

Original languageEnglish (US)
Pages (from-to)1057-1059
Number of pages3
JournalNew England Journal of Medicine
Volume299
Issue number19
DOIs
StatePublished - Nov 9 1978

ASJC Scopus subject areas

  • Medicine(all)

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    Brennan, M. F., Brown, E. M., Marx, S. J., Spiegel, A. M., Broadus, A. E., Doppman, J. L., Webber, B., & Aurbach, G. D. (1978). Recurrent Hyperparathyroidism from an Autotransplanted Parathyroid Adenoma. New England Journal of Medicine, 299(19), 1057-1059. https://doi.org/10.1056/NEJM197811092991909